World Practical Course

European Molecular Biology Organization

Advanced methods for phylogenetic

analysis of molecular sequences

 

 

 

 

 



16 - 22 March | 2009 | Rio de Janeiro| Brazil

Programme (outline)

 

 

The course will begin on Monday March 16th and finish on the morning of Sunday  22nd March.  The course (total ~54 hours) will comprise approximately 18 hours of lectures and round table discussions, 24 hours of computer-based practical sessions, 2 hours of demonstrations and 2 hours of seminars.  All students are expected to give a 10-minute seminar of their work followed by questions.

The practical work is aimed to take students from aligning sequences, to making trees using simple methods, to exploring patterns in sequence data that might mislead their analyses, to the principles and practice of Bayesian and maximum likelihood analyses. 

The students will gain experience in a variety of computer packages and will do some rudimentary scripting. Throughout the course we emphasise the need to be critical in analysing data and interpreting results.

To ensure good contact between the lecturers and students we eat lunch together and have coffee breaks together where discussion is encouraged.  We dine together each evening and have social events including a barbecue and course dinner.   Each student is required to present a 10-minute powerpoint presentation on their work followed by 5-10 minutes of questions, all lecturers and students attend these talks.  Throughout the course we encourage a friendly informal atmosphere.

 

Monday 16th March

 

0900-1000

Introduction – Martin Embley

 

1000-1030

Coffee and discussion

 

1030-1200

Multiple sequence alignment – James McInerney

 

1200-1300

Student introduction and powerpoint presentations (I)

 

1300-1400

Lunch

 

1400-1800

Practical – Alignment and high-throughput alignment methods.

 

1800-1900

Student powerpoint presentations (II).

 

2000  

Dinner

a

 

 

 

Tuesday 17th

 

0900-1000

Distance matrix methods – Martin Embley

 

1000-1030

Coffee and discussion

 

1030-1200

Maximum parsimony – Mark Wilkinson

 

1200-1300

Student powerpoint presentations (III).

 

1300-1400

Lunch

 

1400-1800

Demonstration – PAUP software.

 

1500 - 1800

Practical – phylogenetic analysis using PAUP

 

1800-1900

Student powerpoint presentations (IV).

 

2000  

Dinner

 

 

 

 

Wednesday, 18th March

a

0900-1000

Maximum likelihood – Peter Foster

 

1000-1030

Coffee and discussion.

 

1030-1200

Bayesian inference – Peter Foster

 

1200-1300

Student powerpoint presentations (V)

 

1300-1400

Lunch

 

1400-1800

Practical (likelihood and Bayesian inference).

 

1800-1900

Student powerpoint presentations (VI)

 

2000  

Dinner

 

 

 

 

Thursday, 19th March

a

0900-1000

Protein phylogenetics – TBA

 

1000-1030

Coffee and discussion

 

1030-1200

Protein phylogenetics – TBA

 

1200-1300

Student powerpoint presentations (VII)

 

1300-1400

Lunch

 

1400-1700

Practical – protein phylogenetics.

 

1700-1800

Student powerpoint presentations (VIII).

 

1800-1900

Research seminar - applying phylogenetics to ancient eukaryotic relationships

- Martin Embley

 

2000  

Dinner

 

 

 

 

Friday 20th March

a

0900-1000

Robustness of data and hypotheses – Mark Wilkinson

 

1000-1030

Coffee and Discussion

 

1030-1300

Phylogenetic Supertrees and total evidence –Mark Wilkinson / James McInerey

 

1300-1400

Lunch

 

1400-1800

Practical – phylogenetic supertrees

 

1800-1900

Research seminar - TBA

 

2000

Dinner

 

 

 

Saturday, 21st March

a

0900-1000

High throughput phylogenomics (i)  – James McInerey

 

1000-1030

Coffee and discussion

 

1030-1300

High throughput phylogenomics (ii) – James McInerey

 

1300-1400

Lunch

 

1400-1500

Demonstration – phylogenomic pipeline development.

 

1500-1800

Practical – phylogenomics.

 

2000

Course Dinner

 

 

 

 

Sunday, 22nd March

a

0900-1000

Round table discussion (I)

 

1000-1030

Coffee and discussion

 

1030-1300

Round table discussion (II)

 

1300-1400

 

Lunch

 

1400

Course ends

 
     

 

 

 

 

 

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