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The course will begin on Monday March 16th and finish on the morning of Sunday 22nd March. The course (total ~54 hours) will comprise approximately 18 hours of lectures and round table discussions, 24 hours of computer-based practical sessions, 2 hours of demonstrations and 2 hours of seminars. All students are expected to give a 10-minute seminar of their work followed by questions.
The practical work is aimed to take students from aligning sequences, to making trees using simple methods, to exploring patterns in sequence data that might mislead their analyses, to the principles and practice of Bayesian and maximum likelihood analyses.
The students will gain experience in a variety of computer packages and will do some rudimentary scripting. Throughout the course we emphasise the need to be critical in analysing data and interpreting results.
To ensure good contact between the lecturers and students we eat lunch together and have coffee breaks together where discussion is encouraged. We dine together each evening and have social events including a barbecue and course dinner. Each student is required to present a 10-minute powerpoint presentation on their work followed by 5-10 minutes of questions, all lecturers and students attend these talks. Throughout the course we encourage a friendly informal atmosphere.
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0900-1000
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Introduction – Martin Embley
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Multiple sequence alignment – James McInerney
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Student introduction and powerpoint presentations (I)
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Practical – Alignment and high-throughput alignment methods.
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Student powerpoint presentations (II).
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Tuesday 17th |
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0900-1000
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Distance matrix methods – Martin Embley |
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Coffee and discussion |
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Maximum parsimony – Mark Wilkinson |
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Student powerpoint presentations (III). |
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Lunch |
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Demonstration – PAUP software. |
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1500 - 1800 |
Practical – phylogenetic analysis using PAUP |
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Student powerpoint presentations (IV). |
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Dinner |
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Wednesday, 18th March |
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0900-1000
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Maximum likelihood – Peter Foster |
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Coffee and discussion. |
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Bayesian inference – Peter Foster |
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Student powerpoint presentations (V) |
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Lunch |
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Practical (likelihood and Bayesian inference). |
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Student powerpoint presentations (VI) |
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Dinner |
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Thursday, 19th March |
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0900-1000
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Protein phylogenetics – TBA |
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Coffee and discussion |
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Protein phylogenetics – TBA |
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Student powerpoint presentations (VII) |
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Lunch |
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Practical – protein phylogenetics. |
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1700-1800 |
Student powerpoint presentations (VIII). |
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Research seminar - applying phylogenetics to ancient eukaryotic relationships
- Martin Embley |
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Dinner |
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Friday 20th March |
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0900-1000
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Robustness of data and hypotheses – Mark Wilkinson
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Coffee and Discussion |
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Phylogenetic Supertrees and total evidence –Mark Wilkinson / James McInerey |
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Lunch |
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Practical – phylogenetic supertrees |
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Research seminar - TBA |
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2000 |
Dinner |
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Saturday, 21st March |
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0900-1000
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High throughput phylogenomics (i) – James McInerey |
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Coffee and discussion |
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High throughput phylogenomics (ii) – James McInerey |
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Lunch |
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Demonstration – phylogenomic pipeline development. |
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Practical – phylogenomics. |
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2000 |
Course Dinner |
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Sunday, 22nd March |
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0900-1000 |
Round table discussion (I) |
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1000-1030 |
Coffee and discussion |
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1030-1300 |
Round table discussion (II) |
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1300-1400 |
Lunch |
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1400 |
Course ends |
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