EMBO Courses and Workshops

Programme (overview)

All posters should be put up by the first evening of the conference and will be on display during the whole duration

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Monday 10 May 2010
18.00	Registration at the conference venue Finger food dinner
19.45	Conference Opening Michael Kiebler (Medical University of Vienna, AT)
20.00	Keynote Lecture Joan Steitz (Yale University, Howard Hughes Medical Institute, New Haven, US)
21.00	Welcome drinks

Tuesday 11 May 2010
Session 1: Quality control of nascent transcripts
09.00	Françoise Stutz (University of Geneva, CH) Ubiquitin-mediated mRNP remodeling and surveillance prior to yeast mRNA export
09.30	Lars Steinmetz (European Molecular Biology Laboratory, Heidelberg, DE) Systems genetics of non-coding RNA
10.00	Alain Jacquier (Institut Pasteur, Paris, FR) Hidden transcription in yeast and regulation
10.30	Coffee break
11.00	Domenico Libri (CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette, FR)
11.30	Nick Proudfoot (University of Oxford, UK) Interconnections between gene structure, transcription and pre-mRNA processing
12.00	John Lis (Cornell University, Ithaca, US)
12.30	Catherine Dargemont (IJM CNRS, Paris, FR) Role of ubiquitylation in the coordination between 3’end processing and nuclear export of mRNPs
12.45	Laura Milligan (University of Edinburgh, UK) The Bre5-Ubp3 complex de-ubiquitnates RNA Polymerase II stalled on highly transcribed convergent genes
13.00	Warm lunch at the cafeteria
Session 2: Translation-linked RNA quality control
14.00	Oliver Mühlemann (University of Bern, CH) Charcterization of endogenous mRNAs targeted by NMD
14.30	Elisa Izzauralde (MPI for Developmental Biology, Tübingen, DE)
15.00	Fatima Gebauer (Centre for Genomic Regulation, Barcelona, ES) Cytoplasmic polyadenylation during Drosophila embryogenesis
15.30	Allan Jacobson (University of Massachusetts, Worcester, US)
16.00	Coffee break
16.30	Hervé Le Hir (CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette, FR) The Exon Junction Complex is differentially loaded on spliced junctions
17.00	Lynne Maquat (University of Rochester, US) mRNP Rearrangements During the Pioneer Round of Translation, Nonsense-Mediated mRNA Decay, and thereafter
17.30	Witek Filipowicz (Friedrich Miescher Institut for Biomedical Research, Basel, CH)
18.00	Maiken S. Kristiansen (Centre for mRNP biogenesis and metabolism, Århus, DK) The human core exosome utilizes differentially localized processive ribonucleases: hDIS3 and hDIS3L
18.15	Jernej Ule (MRC LMB, Cambridge, UK)
18.30	Poster session
20.00	Finger food dinner

Wednesday 12 May 2010

Session 3: RNP surveillance, transport and localization
09.00	Rob Singer (Albert Einstein College of Medicine, New York, US)
09.30	Daniel St. Johnston (University of Cambridge, UK) The role of microtubule motors, P bodies and Exu in oskar and bicoid mRNA localisation
10.00	David Tollervey (University of Edinburgh, UK)
10.30	Coffee break
11.00	Isabel Palacios (University of Cambridge, UK)
11.30	Neus Visa (Stockholm University, SE) Co-transcriptional surveillance of mRNA biogenesis in Drosophila
12.00	Gunter Meister (MPI for Biochemistry, Martinsried, DE)
12.30	Gregory Matera (University of North Carolina, Chapel Hill, US) Sm proteins specify germ cell fate by facilitating oskar mRNA localization
12.45	Michael Feldbrügge (Heinrich-Heine University, Düsseldorf, DE) Microtubule-dependent mRNA transport in Ustilago maydis
13.00	Sandwich lunch
Session 4: RNA quality control players: structure and activities, organization in pathways
14.00	Christopher D. Lima (Sloan-Kettering Institute, New York, US) Human and yeast RNA exosomes, insights to RNA processing and decay
14.30	Elena Conti (Max Planck Institute of Biochemistry, Martinsried, DE)
15.00	Irene Bozzoni
15.30	Andrzej Dziembowski (Warsaw University, PL) RNA pathways toward the catalytic centres of the exosome complex
16.00	Coffee break
16.30	Hawei Song (Institute of Molecular and Cell Biology, Proteos, SG) Structure of the Dom34-Hbs1 Complex and implications for its role in No-Go decay
17.00	Peter Lukavsky (MRC LMB, Cambridge, UK) A’-form RNA helices drive microtubule-based mRNA transport in Drosophila
17.15	Julien Henri (Yeast structural genomics IBBMC, Orsay, FR) Dom34-Hbs1 : a complex involved in two quality-control pathways
17.30	Poster competition award
18.15	Departure for Heuriger restaurant by bus
20.00	Official conference dinner

Thursday 13 May 2010

Session 5: RNA quality control at the level of cells and organisms and in diseases
09.00	Andrea Barta (Medical University of Vienna, AT) Analysis of Alternative Splicing and NMD in plants
09.30	TBA
10.00	Javier Caceres (Western General Hospital, Edinburgh, UK)
10.30	Coffee break
11.00	Stuart Peltz (PTC Therapeutics Inc., South Plainfield, US)
11.30	Mathias Hentze (EMBL Heidelberg, DE)
12.00	Karsten Weis (UC Berkeley, US) Global analysis of mRNA turnover in budding yeast
12.15	Dierk Niessing (Helmholtz Zentrum München, DE) The X-ray structure of the neuronal mRNA-transport factor Pur-alpha reveals an unusual RNA-binding domain
12.30	Sandwich lunch and departure

Co-Sponsor
	RNA quality control has only recently emerged as a new field of RNA research and is now one of the most exciting areas of molecular biology. ESF will promote research on this cutting-edge topic through the EUROCORES Programme RNAQuality.....(more)

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Workshop

European Molecular Biology Organization

RNA Quality Control

Programme (overview)

Co-Sponsor