Programme

Friday 4th | Saturday 5th | Sunday 6th


Friday 4th
08.00 - 09.00	Registration
	SESSION I: GENETICS & EVOLUTION
09.00 - 09.35	Introduction
09.35 - 10.10	Pierre Pontarotti Origin and evolution of the adaptive immune system: the case of the MHC class I genes
10.10-10.30	Selected Short Talk: Craig Clements Class Ib MHC: At the crossroads of innate and adaptive immunity
10.30 - 10.45	Coffee Break
10.45 - 11.20	Imre Kacskovics *The role of the MHC class I-related Fc receptor, FcRn, in IgG homeostasis and its implications in therapy*
11.20 - 12.05	Salim I. Khakoo KIR and HLA alleles in disease
12.05 - 12.40	Thomas Boehm *A new role for MHC/peptide presentation*
12.45 - 14.30	Lunch in Congress Venue
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	SESSION II: EXPRESSION & FUNCTION
14.30 - 15.05	Neil J. Bulleid MHC Class I assembly in the Endoplasmic Reticulum
15.05 - 15.40	Paul J. Lehner The regulation of cell surface receptors by viral and cellular ubiquitin E3 ligases
15.40 - 15.55	Selected Short Talk : Louise Boyle A novel MHC class I chaperone
15.55 - 16.15	Coffee Break
16.15 - 16.50	Gennaro De Libero *How the immune system recognizes self and microbial lipid antigen*
16.50 - 17.25	János Matkó MHC Class I antigen presenting function and membrane microdomains: a controversial relationship
17.25 - 18.00	Carla J. Shatz *Neuronal MHC class I and PirB in synapse plasticity and brain circuit tuning*
18.00 - 19.30	Poster Viewing + Cocktail
20.30 - 23.30	Dinner
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Saturday 5th
	SESSION III: FUNCTIONAL INTERACTIONS I
09.00 - 09.35	Klas Kärre *Self as perceived by NK cells: a rheostat model for MHC class I dependent education and tolerance*
09.35 - 10.10	Daniel M. Davis *Synapses and nanotubes in immune cell communication*
10.10-10.30	Selected Short Talk: Luc English Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules
10.30 - 10.45	Coffee Break
10.45 - 11.20	Heinz Wiendl Novel roles of the non-classical MHC molecule HLA-G in immune regulation
11.20 - 12.05	Elaine F. Reed *HLA Class I Signal Transduction Pathways in Endothelial Cells: mechanisms of anti-MHC mediated transplant accommodation and arteriosclerosi*
12.05 - 12.40	Francesco Puppo Immunoregulatory role of classical and non-classical soluble HLA class I antigens
12.45 - 14.30	Lunch in Congress Venue
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	SESSION IV: FUNCTIONAL INTERACTIONS II
14.30 - 15.05	Michael Edidin *Vesicle Trafficking, Dynamic MHC Clusters and Antigen Presentation*
15.05 - 15.40	Werner Held *Modulation of NK cell function by unconventional interactions with MHC class I molecules*
15.40 - 15.55	Selected Short Talk : Sebastian Springer A conformational change induced by the ligand peptide C terminus allows surface transport of MHC class I molecules
15.55 - 16.15	Coffee Break
16.15 - 16.50	Sándor Damjanovich *Significance and message of dynamic patterns of membrane proteins*
16.50 - 17.25	Soldano Ferrone *HLA class I antigen anomalies in malignant diseases*
17.25 - 18.00	Steve Caplan *Regulation of MHC Class I Endocytic Trafficking by C-terminal Eps15 Homology Domain (EHD) Proteins*
18.00 - 19.30	Poster Viewing + Cocktail
20.30 - 23.30	Gala Dinner
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Sunday 6th
	SESSION V: DISEASE ASSOCIATIONS
09.00 - 09.35	José A. López de Castro Molecular basis of HLA-B27 association with spondyloarthritis: towards an integrative perspective
09.35 - 10.10	Paul Bowness *MHC class I dimerization and recognition of cell surface dimers in autoimmunity*
10.10-10.30	Selected Short Talk: Xiang Yu Rao Exploring difference of binding properties between HLA-A and HLA-B which may play an important role in immunodominant CTL response
10.30 - 10.45	Coffee Break
10.45 - 11.20	Robert A. Colbert HLA-B27 Misfolding and Activation of the IL-23/IL-17 Axis
11.20 - 12.05	Fabrizio Spinozzi Role of CD1-restricted lipid-specific T cells in allergic diseases
12.05 - 12.40	Maria de Sousa *Classical MHC class I and HFE at yet another non-immunological interface: iron homeostasis*
12.45 - 14.30	Farewell Lunch	top

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