Programme

Sunday
9th  

18:00 – 23:00  

Welcome
Hotel Couvent des Minimes

18.00

Posters to be displayed

18:00 - 18:05

Introductory Address and Welcome
Jean-Claude Michalski (Lille)

"Encounter with bioethics":
A session affiliated with the BIOTETHED project in collaboration with EMBO
Chair: Jean-Claude Michalski

18:05 - 19:30

Chris Ward (Manchester)
Scientific Importance of Embryonic Stem Cell Research

19:30 – 20:00 

Lewis Wolpert (London)
Ethical Issues of Embryonic Stem Cell Research
Speaker from EMBO Science & Society Programme

20:00 – 20:30

Panel Discussion on ‘Glyconutrients - Science and Myths’
chaired by John Gallagher (Manchester)

20:30 – 23:00

Reception Buffet in Cloisters of Hotel Couvent des Minimes

Monday
1 0th

State of the Art and Perspectives
 Chairs: Tony Merry and Sviatlana Astrautsova

09:00 – 09:40    

Raymond Dwek (Oxford)
Glycoscience – where next ?

09:40 – 10:20  

Pamela Stanley (New York)
Glycoscience in Developmental Biology

Coffee break

11:00 – 11:40  

Ajit Varki (La Jolla)
Uniquely Human Evolutionary Changes in Sialic Acid Biology

11:40 – 12:20     

Gerry Hart ( Baltimore)
Crosstalk Between GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription and Human Disease

12:20 -.12:50     

Guy Lippens (Lille)

High resolution magic angle spinning (HRMAS) NMR of polysaccharides in a heterogeneous environment

Lunch/poster session 1 (Hotel Couvent des Minimes)

Glycosylation defects
Chair: Phillipe Delannoy

15:30 – 16:00    

Jane Hewitt (Nottingham)
Glycosylation and dystroglycan function in muscular dystrophy

16:00 – 16:30   

Terry Butters (Oxford)
Glycolipid Storage disorders

Coffee break

17:00 – 17:30  

Bryan Winchester (London)

The Mucopolysaccharidoses

17:30 – 18:00   

Sergio di Virgilio (Programme Officer Chemistry Marie curie)
Research Training Funding under FP7 – Marie Curie Programmes

18:00 – 18:40   

Cheorl-Ho Kim (Seoul)
Metastatic potential of HBV-derived hepatoma: Hepatitis B viral-specific E-selectin-Sialyl lewis A/X interaction

Hans Bakker (Hannover)
Abolished Xylose incorporation in Glycans and UDP-Glucuronic Acid accumulation in Chinese Hamster Ovary Cells deficient in UDP-xylose Synthase

Alexander Dityatev (Genova)

Synaptic functions of glycans

Gonçalo J. L. Bernardes (Oxford)

Building Synthetic Proteins

Tuesday
11th

Glycosylation and evolution
Chairs: Tony Corfield and Ajit Varki

09.00 – 09:30

Rafael Oriol (Paris)

Phylogeny and Evolution of Fucosyltransferases

09:30 – 10:00 

Vlad Panin (Texas)
Sialylation in protostomes: A perspective from Drosophila development

10:00 – 10:30  

Chris West (Oklahoma City )
Developmental and evolutionary significance of O-glycosylation in Dictyostelium

Coffee break

11.00 – 11h30 

Jose Previato (Rio de Janeiro )
O-glycosylation in the parasite protozoan Trypanosoma cruzi

11:30 – 12.00  

Yann Guérardel (Lille)
Simplification of glycosylation pathways in intracellular parasites

12:00 - 12:30

Angharad O'Leary (Manchester)
Abnormal extracellular matrix from MPS I stromal cells inhibits SDF-1-dependent migration of haematopoetic cells

Anita Stolz (Hannover)
Biological function of the beta4GalNAcTB pilot protein (GABPI) in glycosphingolipid biosynthesis of Drosophila melanogaster

Leena Valmu (Helsinki)

Mass spectrometric profiling of the mesenchymal stem cell glycome

Lunch /Poster Session 2 (Hotel Couvent des Minimes)

Glycosylation and evolution
Chair: Jean-Claude Michalski

14:30 – 15:00

Gerardo Vasta (Baltimore)
Galectins as mediators of developmental and immune mechanisms:
The zebrafish as an alternative animal model to elucidate their biological roles

15:00 – 15:30  

 Iain Wilson (Vienna)
How is a worm more complex than a fly?

Coffee break

Development/Differentiation
Chairs: Cathy Merry and Chris Ward

16:00 – 16:30  

Ken Kitajima (Nagoya)
Involvement of Lewis X-glycans and cadherin in membrane microdomain-mediated blastodermal cell adhesion during gastrulation of medaka fish

16:30 – 17:00 

Yu Yamaguchi (La Jolla )
Genetic dissection of heparan sulfate function in development

17:00 – 17:30

John Aplin (Manchester)
Glycosylation in embryo implantation, placental development and the evolution of viviparity

17:30 – 18:00  

Cathy Merry (Manchester)
Heparan sulphate an essential regulator in embryonic stem cell biology

18:00 – 18:30

Claire Johnson (Manchester)
Fundamental differences in heparan sulphate on human and mouse embryonic stem cells

Isabelle Landrieu (Lille)
Structural and functional characterization of the interaction between cyclophilin b and an heparin derived oligosaccharide

Joachim Bentrop (Karlsruhe)
Molecular evolution and expression of zebrafish St8SiaIII, an alpha-2,8-sialyltransferase involved in myotome development

20:00 – 23:00 

 Meeting Banquet at La Terrasse des Remparts

http://www.terrassedesremparts.fr/restaurant-lille-remparts-gb.html

The Bleu Guide Nord-Pas de Calais reminds us the history of the Porte de Gand:

« Between the 11th and the 19th Century, the city of Lille underwent 7 periods of growth. Each of these periods corresponds to an extension of its fortifications. The vestiges of the fortifications, including la Porte de Gand, date from the 17th century«

Wednesday 12th

Development/Differentiation
Chair: John Gallagher

09:00 – 09:30    

Yvette Van Kooyk (Amsterdam)
Dendritic cells dissecting out the glycocode on immune cells and pathogens

09:30 - 10:00  

Kelly Ten Hagen (Bethesda)
Functional Roles of Protein O-Glycosylation in Drosophila melanogaster

10:00 – 10:30 

Jim Dennis (Toronto)
Co-evolution of N-glycosylation and growth controls in metazoans

Coffee break

11:00 – 11:30  

Rita Gerardy Schann (Hanover)
The dual role of NCAM in steering developmental processes

11:30 – 13:00 

Open forum on the role of glycosylation in development and evolution

Farewell Lunch (Hotel Couvent des Minimes)