Monday, September 10 |
0800 |
Registration |
|
Larischa Palace, Conference Room Foyer |
|
EMT and Development:
Chairperson: Raghu Kalluri |
Larischa Palace, Conference Room |
0830 |
Opening Remarks |
0900 |
Session I (Invited) |
Inaugural Elizabeth D Hay Lecture
Jean-Paul Thiery: Mechanochemistry of cell adhesion in epithelial cell plasticity |
|
0935 |
(Invited) |
Angela Nieto: EMT-related and EMT-independent regulation of cell adhesion and movement by Snail |
 |
1010 |
|
Patrick Humbert: The polarity regulators Scribble and DLG control epithelial migration during development, wound healing and tumourigenesis |
|
1030 |
Coffee & Posters |
Conference Room Foyer |
1100 |
Session II (Invited) |
David McClay: Gene regulatory network states that control EMT. |
Larischa Palace, Conference Room |
1135 |
(Invited) |
Michael Klymkowsky: Conserved and novel features of the NFkβ-Slug-Twist network involved in Xenopus mesoderm formation and EMT |
|
1210 |
|
Michael Murray: Photoactivatable GFP resolves Drosophila mesoderm migration behaviour |
|
1230 |
Lunch and Poster viewing |
Conference Room Foyer | Wierzynek Restaurant / |
|
Cell signalling and EMT (I)
Chairperson: Angela Nieto |
Larischka Palace, Conference Room |
1400 |
Session III (Invited) |
Aristidis Moustakas: Smad proteins of the TGFß pathway instruct a network of transcription factors for the establishment of EMT |
 |
1435 |
(Invited) |
Caroline Hill: Searching for novel regulators of EMT |
|
1510 |
|
Wolfgang Mikulits: PDGF Links TGF-β Signaling to Nuclear β-Catenin Accumulation in Hepatocellular Carcinoma Progression |
|
1530 |
|
Eileen Whiteman: The Transcription Factor Snail Represses Crumbs3 Expression and Disrupts Apico-Basal Polarity Complexes |
|
1550 |
Afternoon Tea and Posters |
Conference Room Foyer |
1630 |
Session IV (Invited) |
John Collard: The Par/Tiam1 polarity complex controls epithelial and mesenchymal properties of epithelial cells. |
Larischa Palace, Conference Room |
1705 |
(Invited) |
Shoukat Dedhar: Regulation of EMT and Wnt signaling by Integrin-Linked Kinase |
|
1740 |
|
William Schiemann: EMT and Oncogenic Signaling by TGF-ß in Mammary Epithelial Cells |
|
1800 |
|
Poster Session / EpiPlast Carcinoma Committee Meeting |
 |
Tuesday, September 11 |
|
EMT and Cancer (I)
Chairperson: Antonio García de Herreros |
Larischa Palace, Conference Room |
830 |
Session V (Invited) |
Paolo Comoglio: Invasive growth: a MET-driven genetic programme for cancer and stem cells |
|
905 |
(Invited) |
Don Newgreen: EMT in the neural crest model: Does functional manipulation of adhesion and cytoskeletal systems reset the sensitivity to pro-EMT growth factors? |
|
940 |
|
Greg Goodall: The microRNA-200 family regulates the E-cadherin repressors, ZEB1/deltaEF-1 and SIP1/ZEB2 and EMT |
|
1000 |
Coffee & Posters |
Conference Room Foyer |
1030 |
Debate |
EMT-MET cycles in tumors: Amparo Cano, Gerhard Christofori, Pierre Savagner and Erik (Rik) Thompson |
Larischa Palace, Conference Room |
1130 |
Session VI (Invited) |
Gerhard Christofori: Distinct mechanisms of tumor invasion and metastasis |
Larischa Palace, Conference Room |
1205 |
(Invited) |
Erik (Rik) Thompson: Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the Human Breast Cancer Stem Cell Phenotype and Subclassify Human Breast Cancers
|
 |
1240 |
Lunch and Poster viewing Wierzynek Restaurant / |
Conference Room Foyer |
|
EMT and Cancer (II)
Chairperson: John Collard |
Larischa Palace, Conference Room |
1415 |
Session VII (Invited) |
Amparo Cano: Understanding the role of Snail factors and other EMT regulators in tumour progression |
|
1450 |
(Invited) |
Thomas Brabletz: Malignant progression in colorectal cancer: EMT, β -Catenin & cancer stem cells |
 |
1525 |
|
Andreas Eger: The transcription factor ZEB1 promotes tumor progression by repressing master regulators of epithelial differentiation |
|
1545 |
Afternoon Tea and Posters |
Conference Room Foyer |
1615 |
Session VIII (Invited) |
Avri Ben-Ze’ev: Cell motility at the invasive front of tumors: The role of novel Wnt/ß-catenin target genes |
|
1650 |
(Invited) |
Arne Östman: PDGF-dependent cancer fibroblasts and pericytes as novel cancer drug targets |
|
1725 |
|
Laura Rosano: β -Arrestin-1 as messenger of endothelin A receptor-driven >β-catenin signaling pathway and epithelial to mesenchymal transition: implication for an effective combined therapy in ovarian cancer |
 |
1745 |
|
Hector Peinado: LOXL2 as a player in epidermal homeostasis and early marker of squamous cell carcinomas |
|
1805 |
|
Poster Session / TEMTIA Annual General Meeting |
1900 |
|
Conference Dinner |
Folwark Zalesie |
Wednesday, September 12 |
|
Physiological aspects of EMT
Chairperson: Aristidis Moustakas |
Larischa Palace, Conference Room |
0830 |
Session IX (Invited) |
Pierre Savagner: Slug regulates early epithelial differentiation by maintaining a metastable phenotype |
|
0905 |
(Invited) |
Raghu Kalluri: The Effects of BMP-7 on EndMT and Cardiac Fibrosis |
|
0940 |
|
Jiri Zavadil: Gene Regulation Network Analysis Suggests Epigenetic Mechanism for Silencing of TIMP3 in EMT |
 |
1000 |
Coffee & Posters |
Conference Room Foyer |
1030 |
Debate |
EMT in development and physiology: Michael Klymkowsky, Raghu Kalluri and Angela Nieto |
|
1130 |
Session X (Invited) |
Raymond Runyan: Regulation of EMT in the atrioventricular canal of the developing heart |
|
1205 |
(Invited) |
Claire Sharpe: Delineation of GTPase pathways in EMT: A role for every Rho? |
|
1225 |
|
Andrew Garrod: New concepts in desmosomal adhesion and their implications for EMT |
|
1245 |
Lunch/Poster Viewing |
Conference Room Foyer |
|
Cell signalling and EMT (II)
Chairperson: Paolo Comoglio |
1415 |
Session XI (Invited) |
Lionel Larue: The role of IGF/AKT pathways in the induction of epithelium mesenchyme transition |
 |
1450 |
(Invited) |
Antonio García de Herreros: The adhesion junction protein E-cadherin plays a central role in the process of epithelial morphogenesis |
|
1525 |
(Invited) |
Geert Berx: Functional analysis of EMT-inducing transcription factors in invasion and metastasis |
|
1600 |
Concluding remarks, and Invitation to the 4th EMT Meeting in 2009 |