About the Practical Course
This course is aimed at researchers who are actively investigating the molecular and cellular basis of physiological and disease mechanisms and who are keen to harness the power of model organisms to advance their research.
Many of the mechanisms that control development and physiological function are remarkably well-conserved within the animal kingdom, widely validating the use of several key species as models for understanding many aspects of human biology.
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Main Objectives
1. To provide students with hands-on experience of working with a range of different non-mammalian model organisms. 2. To teach a range of molecular, genetic and other experimental techniques used for dissecting physiological mechanisms and human disease processes in model organisms. 3. To provide students with opportunities to evaluate the particular strengths and limitations of the different model organisms introduced on the course.
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Zebrafish, Drosophila, chick and C. elegans are particularly amenable to the use of molecular, genetic and embryological techniques that have revolutionised our understanding of animal development. The extensive genomic similarities between these model organisms and mammals, together with features such as genetic tractability, optical transparency, rapid development and ease of access for physical manipulation, have also made these organisms highly suited to the analysis of physiology and disease processes. |
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We look forward to welcoming you to Sheffield! The Organisers |
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