Practical Course

European Molecular Biology Organization

Structure, dynamics and function of biomacromolecules by solution NMR






27 July - 3 August| 2009 |Garching | Germany

About the Practical Course

The intention of the course is to provide practical training in important aspects of using solution state NMR spectroscopy for studying the structure, dynamics and function of biomolecular macromolecules. The emphasis will be on setting up experiments on the spectrometer (optimizing parameters, pulse programs), on processing and analyzing the NMR data and on structure calculations in a hands-on fashion.

It is impossible to teach all the necessary theoretical background of modern NMR experiments in a few days. Therefore, the course is aimed at PhD students and postdocs who have some working knowledge of NMR theory, i.e. product operator formalism, and who understand the basic principles of NMR pulse sequences. Possible candidates should have the level of knowledge of students that have participated in a past "Advanced NMR" EMBO lecture course on NMR theory organized by Boelens, Oschkinat and Griesinger.


Pulse sequences: theory, design, practical set-up and use

Multidimensional data processing and data analysis

Relaxation: theory, experiments, data analysis

Residual dipolar couplings: theory, experiments, data analysis

Structure calculation and validation: proteins and RNA

Protein-ligand interactions

NMR of high molecular weight systems, TROSY etc.

We look forward to seeing you in Garching!

The Organizing Committee

Download/view poster

European Molecular Biology Organisation (EMBO) | Meyerhofstrasse 1 | 69126 Heidelberg | Germany