Monday 20th June 2011

08.30-09.00

Registration (educational session)

09.00-09.40

Matthias Mann – Max Planck Institute for Biochemistry, Martinsried, Germany

“MaxQuant and Perseus for the bioinformatic analysis of quantitative proteome data”

09.40-10.20

Rolf Apweiler – European Bioinformatics Institute, Hinxton, UK

"Using proteomic data resources to identity novel cancer targets"

10.20-10.40

Coffee

10.40-11.20

Aedin Culhane – Dana-Farber Cancer Institute, Boston, USA

“Using curated gene information in statistical meta-analysis of genomics data”

11.20-12.00

Fredrik Ponten – Uppsala University, Sweden

12.00-13.00

Lunch (educational session attendees only)

12.30-13.15

Registration (main program)

13.20-13.30

Welcome and opening remarks (William Gallagher)

13.30-14.20

Opening Keynote Lecture: Matthias Mann – Max Planck Institute for Biochemistry, Martinsried, Germany

"Super-SILAC technology to accurately quantify the cancer proteome"

14.20-14.55

Fredrik Ponten – Uppsala University, Sweden

"A Human Protein Atlas for profiling normal and cancer cells and tissues"

14.55-15.20

Proffered Talk 1: Laoighse Mulrane – UCD Conway Institute, Dublin, Ireland

“MiR-187 is a marker of poor prognosis in estrogen receptor-positive breast cancer”

15.20-15.50

Coffee/Trade exhibit

15.50-16.25

Laura Beretta – Fred Hutchinson Cancer Research Center, Seattle, USA

"Hepatocellular carcinoma proteomics"

16.25-17.00

Connie Jimenez – VUmc-Cancer Center Amsterdam, The Netherlands

"Label-free mass spectrometry-based proteomics for biomarker discovery in murine and human cancer"

17.00-17.25

Proffered Talk 2: Sara Zanivan – Beatson Institute for Cancer Research, Glasgow, United Kingdom

“In vivo quantitative proteomics and phosphoproteomics of skin cancer development”

17.25-17.50

Proffered Talk 3: Francois-Michel Boisvert – University of Dundee, United Kingdom

“A quantitative spatial proteomics analysis of proteome turnover in human cancer cells”

17.50

Welcome Reception and Trade Exhibit

Tuesday 21st June 2011

Session 2 - Cancer stem cells and developmental model systems

09.00-09.35

Tony Whetton – University of Manchester

“Proteomic studies on normal and leukaemic stem cells reveal novel regulatory pathways in drug responses”

09.35-10.10

Xiaoyan Jiang – University of British Columbia, Vancouver, Canada

“A novel AHI-1-BCR-ABL-JAK2 interaction complex mediates cellular resistance to tyrosine kinase inhibitors in chronic myeloid leukemia stem cells”

10.10-10.35

Proffered Talk 4: Leonie Norris – University of Leicester, United Kingdom

“A strategy for label-free quantification of protein biomarkers in cancer stem-like cells”

10.35-11.05

Coffee/Trade exhibit

Eileen Furlong – European Molecular Biology Laboratory, Heidelberg, Germany
“Transcriptional networks during development - Deciphering the code”

11.40 - 12.05

Proffered Talk 5: Veronica Miguela – Instituto de Neurociencias, Alicante, Spain
“Looking for new partners in crime for the tumorigenic activity of Pipsqueak”

12.05-12.50

Lunch/Trade exhibit

Poster Session 1

12.50 - 13.50

Authors of even numbered posters in attendance

13:50 - 14:15

Proffered Talk 6: Safia Thaminy – Institute of Molecular Systems Biology, Zurich, Switzerland

“Integrated proteomic and siRNA screen analysis to study the migratory phenotype of breast cancer cell lines”

(Abstract selected for emerging investigator award)

14.15-14:40

Proffered Talk 7: Tamar Geiger – Max Planck Institute of Biochemistry, Martinsried, Germany

“A proteomic portrait of human breast cancer progression”

14.40 - 15.05

Proffered Talk 8: Bodo Lange – Max-Planck Institut für molekulare Genetik, Berlin, Germany

“Functional characterisation of a centrosome protein interaction network relating to centrosome biogenesis and aberration in cancer cells”

15.05 - 15.30

Proffered Talk 9: Adam Byron – University of Manchester, United Kinddom

“Proteomic analysis of integrin adhesion signalling in cancer cells”

15.30 - 15.55

Proffered Talk 10: Aaron Robitaille - Biozentrum, University of Basel, Switzerland

“Quantitative analysis of the mTOR signaling network”

(Abstract selected for emerging investigator award)

15:55 - 16:25

Coffee/Trade exhibit

16.25-17.200

Stephen Pennington – University College Dublin, Ireland
“Cancer Proteomics: Promise or Progress?”

1700-17:35

Michael Gillette – Broad Institute of MIT and Harvard, Cambridge, USA

“Progress toward a biomarker discovery-to-development pipeline in clinical proteomics”

17.35 - 18.10

Ruth Hüttenhain – Institute for Molecular Systems Biology, ETH Zurich, Switzerland

“Cancer genetics-guided discovery of protein biomarkers and their SRM-based verification in plasma”

18.10 - 18.35

Proffered Talk 11: Yue Fan – UCD Conway Institute, Dublin, Ireland

“Label-free LC-MS/MS and MRM development for discovery and verification of biomarkers for prostate cancer”

Wednesday 22nd June 2011

09.00-09:45

Address by Minister of State

09.45 - 10.20

Emmanuel Barillot – Institut Curie, Paris, France

"Modeling biological networks involved in tumor progression"

10.20 - 10.55

Rune Linding – Technical University of Denmark, Lyngby, Denmark

"Cancer network medicine and cellular information processing"

10.55 - 11.25

Coffee/Trade exhibit

11.25 - 12.00

Ulrike Eggert– Dana Farber Cancer Institute, Boston, USA

"A combined chemical genetic/RNAi approach to study cell signalling"

12.00 - 12.35

Christie Sers– Charité Universitätsmedizin Berlin, Germany 

"Systems biology in predictive medicine"

12.35 - 13.25

Lunch/Trade exhibit

Poster Session 2

13.25 - 14.25

Authors of odd numbered posters in attendance

14.25 - 15.00

Andrew Emili – University of Toronto, Toronto, Canada

"Interaction networks and chromatin-related protein complexes in cancer"

15.00 - 15.35

Walter Kolch– Systems Biology Ireland, Dublin, Ireland

“Signalling networks and systems biology”

15.35 - 16.10

Michael Cusick – Dana-Farber Cancer Institute, Boston, USA

16.10 - 16.40

Coffee/Trade exhibit

16.40 - 17.15

Igor Stagljar – University of Toronto, Canada

"Protein interaction networks regulating cell signalling in cancer"

17.15 - 17.40

Proferred Talk 12: Anthony Coolen –King's College London, United Kingdom

“Non-equilibrium statistical mechanics of signalling in large protein interaction networks”

evening

 Conference Dinner and Entertainment

Thursday 23rd June 2011

09.00-09.35

Søren Brunak– Technical University of Denmark, Kongens Lyngby, Denmark

“Integrating healthcare sector data with molecular data in cancer”

09.35-10.10

Anne-Lise Børresen-Dale – The Norwegian Radium Hospital, Oslo, Norway

"Integrated genomics of breast cancer"

10.10-10.40

Coffee/Trade exhibit

10.40-11.15

Aedin Culhane – Dana-Farber Cancer Institute, Boston, USA

“Computational Discovery of the Hallmarks of Cancer through Meta Gene Set Analysis”

11.15-11.50

Lodewyk Wessels – Netherlands Cancer Institute, Amsterdam, The Netherlands

“Oncogenic pathway identification through itegration of diverse, same sample data sources”

11.50-12.50

Lunch/Trade exhibit

12.50-13.25

Serhiy Souchelnytskyi – Karolinska Biomics Center, Stockholm, Sweden

"Personalized medicine and cancer proteomics"

13.25-14.00

Tony Ng - King's College London, UK
“Use of nanoscopic cancer tissue imaging, gene bioinformatics and mathematical modelling to predict the metastatic outcome of breast cancer sufferers“

14.00-14.25

Proferred Talk 13: Steven Kornblau – U. Texas M.D. Anderson Cancer Center, Houston, USA

“Proteomic analysis of the signaling pathways underlying acute myeloid leukemia”

14.25-14.55

Coffee/Trade exhibit

14.55-15.30

William Gallagher – University College Dublin, Dublin, Ireland
“Bridging the translational divide: converting omic datasets into clinical relevant assays”

15.30-16.20

Closing Keynote Lecture: Dario Neri – Institute of Pharmaceutical Sciences ETH Zurich, Switzerland

"Vascular tumor targeting: from target discovery to clinical trials"

16.20-16.25

Closing Remarks (William Gallagher)