Conference Series

European Molecular Biology Organization

Cellular Signaling &

Molecular Medicine

 

 

 

 

 



May 21 - 26 | 2010 | Cavat (Dubrovnik)| Croatia

Programme (FINAL)

 

***  DOWNLOAD FINAL PROGAMME:   (word.doc)  (pdf)

 

Friday May 21

 

16:00

Arrival and Registration

20:00

Welcome Reception

   

Saturday May 22

 

8:50-9:00          

Opening remarks

   

 

Session I
Controlling Protein Conformations and Interactions

 

Chairperson: Tony Pawson

   

9:00-9:30

Ivan Dikic (Germany) European Association of Cancer Research Sponsored Lecture

 

Ubiquitin-mediated regulation of NF-κB activation and autophagy

   

9:30-10:00

Tony Pawson (Canada)

 

Proteomic analysis of bidirectional signaling networks

   

10:00-10:20

Jean Paul Borg (France)

 

Identification of a promigratory signaling cassette associated to the Vangl2 polarity receptor

   

10:20-11:00

Coffee Break

   

11:00- 11:20

Angel F Lopez (Australia)

 

A molecular basis for the pleiotropic biological activities of cytokine receptors

   

11:20-11:40

Herve Bazin (France)

 

Homogeneous Time Resolved Fluorescence Technique for Study and Imaging of Receptor oligomerization

   

11:40-12:10

Tony Hunter (USA)

 

Signal transduction in DNA damage and cancer

   

12:30-13:30

Lunch

   

 

Session II

Inflammation and Disease

 

Chairperson: Michael Karin

   

14:00-14:30

Michael Karin (USA)

 

Signaling pathways that link inflammation, metabolism and cancer

   

14:30-14:50

Henning Walczak (UK)

 

The role of linear ubiquitylation in TNF receptor superfamily signal transduction

   

14:50-15:20

Frances Balkwill (UK)

 

Inflammatory Cytokines and Autocrine Tumor-Promoting Networks

   

15:20-16:00

Coffee Break

   

16:00-16:30

Dan Littman (USA)

 

A cryptic innate sensor for HIV in human dendritic cells

   

16:30-17:00

Erwin Wagner (Spain)

 

Inflammatory skin disease and the role of Jun/AP-1

   

17:30 - 19:00

Poster Session I (Odd Numbers)

   

18:00-18:30

Meet the Editor

   

Sunday May 23, 2010

 

   

 

Session III

Signaling in Vascular Biology and Disease

 

Chairperson: Manuela Baccarini

   

9:00-9:30

Ralph Adams (Germany)

 

Regulation of angiogenesis by endothelial cell-cell interactions

   

9:30-10:00

Amparo Acker-Palmer (Germany)

 

EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis

   

10:00-10:30

Elisabetta Dejana (Italy)

 

The role of canonical Wnt signalling in vascular development

   

10:30-11:00

Coffee Break

   

11:00-11:30

Manuela Baccarini (Austria)

 

Role of Raf in angiogenesis

   

11:30-11:50

Beate Lichtenberger (Austria)

 

Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development

   

11:50-12:20

Ellen Van Obberghen-Schilling (France)

 

Deciphering the mechanisms of fibronectin fibrillogenesis and its role in vascular endothelial cell plasticity

   

12:30-13:30

Lunch

   

 

Session IV

Stem Cells

 

Chairperson: Erwin Wagner

   

14:00-14:30

Fiona Watt (UK)

 

The epidermal stem cell microenvironment

   

14:30-15:00

Emmanuelle Passegue (USA)

 

The dark side of hematopoietic stem cell quiescence

   

15:00-16:00

Coffee Break

   

16:00-16:20

Pierre Marie (France)

 

Priming integrin alpha5 in human mesenchymal stem cells promotes osteoblast differentiation and osteogenesis

   

16:20-16:40

Latifa Bakiri (Spain)

 

ES-derived tet-regulated transgenic mice to study FOS/AP-1 functions

   

16:40-17:10

Andreas Trumpp (Germany) MERCK SERONO Sponsored Lecture

 

Waking up Dormant Stem Cells

   

17:30 - 19:00

Poster Session II (Even Numbers)

   
   

Monday May 24

 

 

Keynote Lecture

 

Chairperson: Ivan Dikic

   

9:00- 9:45

Joseph Schlessinger (USA)

 

Cell signaling by receptor tyrosine kinases; from molecules to cancer therapy

   

 

Session V

Cell Adhesion and Movement

 

Chairperson: Margaret Frame

   

9:45- 10:15

Sara Wickström (Germany)

 

Integrin signaling regulates caveolar traffic

   

10:15-10:35

Guido Posern (Germany)

 

MALfunction on the EGFR-MAPK cascade and during non-invasive cell migration through target gene induction

   

10:35-11:00

Coffee Break

   

11:00-11:30

Peter Friedl (NL)

 

Collective cancer invasion in vivo: role of integrins in invasion, survival and resistance to radiotherapy

   

11:30-11:50

Corinne Albiges-Rizo (France)

 

Dynamics of adhesive structure through integrin activation and extracellular matrix remodeling

   

11:50-12:20

David Calderwood (USA)

 

Integrin-cytoskeletal interactions in cell migration and signaling

   

12:30-13:30

Lunch

   

14:00

Boat trip in the afternoon, guided tour and evening free in Dubrovnik

   

Tuesday May 25

 

   

 

Session VI
Control of Adaptive Immunity

 

Chairperson: Arthur Weiss

   

9:00- 9:30

Facundo Batista (UK)

Lymphocyte activation and tonic signalling: visualizing a role for the cytoskeleton using high-resolution imaging

   

9:30-9:50

Tomas Brdicka (Czech Republic)

 

Nvl: transmembrane adaptor protein involved in MHCII signaling

   

9:50-10:20

Bernard Malissen (France)

 

How T cells keep protein tyrosine kinase activity in check

   

10:20-11:00

Coffee Break

   

11:00-11:30

Michael Reth (Germany)

 

Regulation and autoinhibition of the B cell antigen receptor on resting B cells

   

11:30-11:50

Vicenzo Di Bartolo (France)

 

The protein kinase HPK-1 negatively regulates T cell activation by reducing the stability of TCR-induced signaling protein complexes

   

11:50-12:20

Arthur Weiss (USA)

 

Turning T cell antigen receptor signaling pathways off and on with genetically controlled protein tyrosine kinase inhibitors

   

12:30-13:30

Lunch

   

 

Session VII
Disease Microenvironment and Tumor Progression

 

Chairperson: Valerie Weaver

   

14:00-14:30

Margaret Frame (UK)

 

Targeting invasion and metastasis

   

14:30-14:50

Michel Aurrand-Lions (France)

 

GRASP55 - new intracellular adaptor of Junctional Adhesion Molecule family controls their stability and trafficking

   

14:50-15:20

Silvia Giordano (Italy)

 

Molecular mechanisms sustaining Oncogene Addiction and resistance to inhibition in tumor cells

   

15:20-16:00

Coffee Break

   

16:00-16:30

Valerie Weaver (USA)

 

 

16:30-16:50

Christoph Lamaze (France)

 

A New Role for Caveolae in Mechanosensing

   

16:50-17:20

Raghu Kalluri (USA)

 

Diverse roles of tumor associated mesenchymal cells in cancer progression and metastasis

 

 

17:30 - 19:00

Poster Session III (All Numbers)

   

20:00

Gala dinner

 

Poster Award Presentation

   

Wednesday May 26

 

 

Departure

   

 


 

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