EMBO Courses and Workshops

Programme (outline)

Tuesday, 14th July
15:00	Registration - Lobby
19:00	Lamoraalzaal Opening and keynote address: Tony Hunter
20:00	Pub at Zuiderduin Welcome reception and small buffet

Wednesday, July 15
09:00-12:15	Lamoraalzaal Session 1: Disease chair: Tony Tiganis
09:00	Ben Neel Tyrosine phosphatases in health and disease
09:30	Mathieu Bollen Role of NIPP1-associated PP1 in chromatin signaling and tumor growth
10:00	Ari Elson PTP Epsilon inhibits challenge-induced obesity by down-regulating leptin signaling in the hypothalamus
10:15	Antje Gohla Identification of a heteromeric Chronophin phosphatase complex regulated by calcium
10:30	Break - Lobby
10:45	Maria Kontaridis Noonan Syndrome, LEOPARD Syndrome and the link to Congenital Heart Defects and Disease
11:15	Edgar da Cruz e Silva PP1 inhibition by Aβ and aluminum: a putative pathological mechanism underlying Alzheimer's disease
11:45	Rekha Panchal Immune protection against multiple lethal pathogens by modulation of a protein tyrosine phosphatase
12:00	Lydia Tabernero New phosphoinositide bacterial phosphatases as targets in infectious diseases
12:15	Lunch - Zuiderduin restaurant
13:00-15:00	Poster session 1 - Lobby
15:00-18:15	Lamoraalzaal Session 2: Cancer and cell cycle chair: Egon Ogris
15:00	David Brautigan Protein phosphatase-6 in the dna damage response
15:30	Dmitry Bulavin Wip1-p38MAPK signalling pathway controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age
16:00	Wiljan Hendriks Impaired PTPN13 activity in spontaneous and HPV-induced squamous cell carcinomas potentiates the ErbB2 signal transduction pathway
16:15	Douglas Kellogg The Wee1 kinase and protein phosphatase 2A modulate Cdk1 activity during early mitosis
16:30	Break - Lobby
16:45	Michel Tremblay Protein tyrosine phosphatases in human cancer
17:15	Jorge Torres A specific form of protein phosphatase 2A regulates the association of the Anaphase Promoting Complex with mitotic microtubules
17:45	Seth Rubin A protein phosphatase 1 docking interaction is required for Retinoblastoma protein dephosphorylation
18:00	Anna Sablina Mechanisms of PP2A-mediated transformation
18:00-20:00	Dinner - Zuiderduin restaurant
20:00-22:00	Lamoraalzaal Session 3: Structure chair: Anton Bennett
20:00	Stefan Knapp Large-scale structural analysis of the classical human protein tyrosine phosphatome
20:30	Stefan Szedlacsek Interface Analysis of the Complex between ERK2 and PTP-SL
20:45	Nicola Beresford Inhibition of MPTPB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages
21:00	A. Radu Aricescu A close look at the receptor protein tyrosine phosphatase ectodomains
21:30	Yongna Xing Toward a Structural Paradigm of PP2A Regulation

Thursday, July 16th

09:00-12:15	Lamoraalzaal Session 4: Function chair: Ben Neel
09:00	Nick Tonks Functional analysis of the PTPs
09:30	Anne-Claude Gingras Charting the kinase-phosphatase interactomes
10:00	Frank Böhmer Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B
10:15	Andrei Vacaru Unexpected elements in Src - RPTPalpha association
10:30	Break - Lobby
10:45	Anton Bennett Physiological Roles of MAP Kinase Phosphatases
11:15	Michael Tsang Zebrafish chemical screens identify a small molecule inhibitor of Dusp6
11:45	Takayasu Kobayashi Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity
12:00	Rafael Pulido Functional study of MKP-3 cleavage by the apoptotic protease caspase-3
12:15	Lunch - Zuiderduin restaurant
13:00-15:00	Social activities (reservation requested)
15:00-18:15	Lamoraalzaal Session 5: Signaling I chair: Mathieu Bollen
15:00	Catherine Pallen Roles of PTP alpha in immune cell responses
15:30	Maikel Peppelenbosch Employing peptide arrays for understanding action and function of protein phosphatases
16:00	Benoit Boivin A novel tumor suppressor role for RPTPα in ErbB2- induced cell migration and invasion
16:15	Aimin Peng Repo-man controls a Protein Phosphatase 1-dependent threshold for DNA damage checkpoint activation
16:30	Break - Lobby
16:45	Tony Tiganis Turning off T cells
17:15	David Virshup Regulation of Signaling in the Wnt Pathway
17:45	Maria Kleppe Homozygous deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia
18:00	Vincent Tagliabracci Glycogen Phosphorylation and Lafora Disease
18:15-20:30	Egmond aan Zee Dinner on your own (not included in the programme)
20:30-22:00	Lamoraalzaal Session 6: keynotes (sponsored by: Cancer Genomics Centre) chair: Jeroen den Hertog
20:30	Tim Hunt Protein phosphatases and the control of mitosis: very important, extremely puzzling
21:15	Albert Heck Phosphoproteomics: promises, deliverables and challenges

Friday, 17th July

09:00-12:15	Lamoraalzaal Session 7: Signaling II chair: Nick Tonks
09:00	Boudewijn Burgering Regulation of FOXO by reactive oxygen: balancing lifespan and disease
09:30	Gen-Sheng Feng Shp2 Regulation of ES Cell Differentiation and Pancreatic beta-Cell Function
10:00	Jeroen Frijhoff Redox regulation of protein tyrosine phosphatases by p66Shc
10:15	Wei Zheng RPTP LAR positively regulates the PDGF beta-receptor signaling
10:30	Break - Lobby
10:45	Zhong-Yin Zhang Chemical Biology and Signaling Mediated by Tyrosine Dephosphorylation
11:15	Mitsuhiro Yanagida Requirement of CTD Phosphatase Fcp1 and type 2A-like phosphatase inhibitor Sds23 for nutritional control of quiescence and proliferation in S. pombe
11:45	Anna dePaoli-Roach p38MAPK, but not PP1G/RGL or Inhibitor-1, in Epinephrine control of Glycogen metabolism
12:00	Daimark Bennett PNUTS-PP1 antagonises Jil-1/MSK to regulate interphase histone H3 phosphorylation
12:15	Lunch - Zuiderduin restaurant
13:00-15:00	Poster session 2 - Lobby
15:00-18:15	Lamoraalzaal Session 8: Regulation chair: Irute Meskiene
15:00	Jean-Antoine Girault A phosphatase cascade by which natural rewards and drugs of abuse regulate nucleosomal response
15:30	Thorsten Heinzel The interplay of acetylation and phosphorylation in the regulation of STAT1 activity
16:00	Balázs Szöőr A glycosomal DxDxT phosphatase, TbPIP39, is a substrate of TbPTP1 in the T. brucei differentiation signalling pathway
16:15	Jukka Westermarck PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma
16:30	Break - Lobby
16:45	Erwin Grill Regulators of PP2C activity are phytohormonesen
17:15	Tzu-Ching Meng Protein tyrosine phosphatase and kinase coordinate to regulate actin organization
17:45	Arne Östman 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling by oxidation of protein tyrosine phosphatases
18:00	Eva Nievergall PTP1B regulates Eph receptor phosphorylation and traffic
19:00	Conference dinner - Restaurant "de Zilte Zoen"

Saturday, 18th July

09:00-12:15	Lamoraalzaal Session 9 : Development chair: Zhong-Yin Zhang
09:00	Veerle Janssens A novel biological function of the PP2A PR130/B”α1 complex in cell migration and adhesion
09:30	Irute Meskiene Stress and plant development control by PP2C phosphatases in Arabidopsis
10:00	Mark van Eekelen Functional analysis of classical protein tyrosine phosphatases in the zebrafish genome
10:15	Angus Nairn Regulation and Function of Protein Phosphatase 1 isoforms
10:30	Break - Lobby
10:45	Andy Stoker Regulation of spinal neurogenesis by PTPγ
11:15	Maud Martin Identification of the first developmental function for PP2A Bα regulatory subunit: Bα regulates migration-related angiogenesis through the control of class IIa HDAC7 activity
11:30	Sheila Harroch Soluble RPTPzeta/Phosphacan regulates OPC development
11:45	Egon Ogris A novel approach towards the identification of protein phosphatase 2A (PP2A) substrates
12:15	Departure of Delegates

practical courses | workshops | conference series | world activities | joint activities | plenary lectures|

Conference Series

European Molecular Biology Organization

EUROPHOSPHATASES 2009
Protein phosphatases in
development and disease

Programme (outline)

practical courses | workshops | conference series | world activities | joint activities | plenary lectures|

Conference Series

European Molecular Biology Organization

EUROPHOSPHATASES 2009 Protein phosphatases in development and disease

Programme (outline)

EUROPHOSPHATASES 2009
Protein phosphatases in
development and disease