Chair: Laszlo Nagy

University of Debrecen, Hungary

Peter Fraser

Chromatin and Gene Expression Laboratory, Babraham Institute, Cambridge, UK

TRANSCRIPTIONAL INTERACTOME; SPATIAL NETWORKS OF CO-REGULATED GENES

Christopher K. Glass

Department of Cellular & Molecular Medicine, University of California, San Diego, USA
NUCLEAR RECEPTOR TRANSREPRESSION PATHWAYS THAT REGULATE INFLAMMATION

Inez Rogatsky

HSS and Weill Medical College of Cornell University, New York, USA
GLUCOCORTICOID INHIBITION OD THE INTERFERON SIGNALING PATHWAY (Short talk

Peter Tontonoz

Howard Hughes Medical Institute, UCLA, Los Angeles, CA, USA
CONTROL OF CHOLESTEROL HOMEOSTASIS BY LXRs

Chair: Philippe Claude Lefebvre

Inserm-Institut Pasteur de Lille, Lille France

Bruce Spiegelman

Department of Cancer Biology, Harvard Medical School, Boston, USA
TRANSCRIPTIONAL CONTROL OF PREADIPOCYTE DETERMINATION AND PPARg BY Zfp423

Vengalil Krishna Chatterjee

University of Cambridge, Cambridge, UK
A NOVEL MUTATION IN THE HUMAN PPARY LIGAND BINDING DOMAIN IN SEVERE INSULIN RESISTANCE (Short talk)

Catherine Postic

Département d’Endocrinologie, Métabolisme et Cancer, Institut Cochin, Paris, France
MOLECULAR CONTROL OF THE LIPOGENIC PATHWAY IN LIVER: CONTRIBUTION OF NUCLEAR
RECEPTOR LXR AND TRANSCRIPTION FACTORS ChREBP, SREBP-1c

Ronald M. Evans

Gene Expression Laboratory, Salk Institute for Biological, Studies,San Diego, California, USA
NUCLEAR RECEPTORS AND AMPK – RESETTING METABOLISM

Noa Noy

Department of Pharmacology, Case Western Reserve University School of Medicine Cleveland, Ohio, USA
RETINOIDS IN ADYPOCITE BIOLOGY

Jan Peter Tuckermann

Leibniz Institute for Age Research - Fritz Lipmann Institute,Jena, Germany
GLUCOCORTICOIDSSUPPRESS BONE FORMATION BY ATTENUATING OSTEOBLAST DIFFERENTIATION
VIA THE MONOMERIC GLUCOCORTICOID RECEPTOR (Short talk)

Kristina Schoonjans

Institut interfacultaire de Bioingénierie, Ecole Polytechnique Fédérale de Lausanne, Switzerland
BILE ACID SIGNALING AND CONTROL OF METABOLISM

Chair: Vincent Giguere

Goodman Cancer Centre, Montreal, Canada

Xiang-Dong Fu

Department of Cellular & Molecular Medicine,University of California,San Diego, USA
REPROGRAMMING THE ANDROGEN RECEPTOR IN PROSTATE CANCER CELLS

Eric Kalkhoven

Dept. Metabolic and Endocrine Diseases, UMC Utrecht, The Netherlands
PPARgamma REGULATES EXPRESSION OF THE ANTI-LIPOLYTIC G-PROTEIN-COUPLED
RECEPTOR 81 (GPR81/Gpr81) (Short talk)

Balint L. Balint

University of Debrecen, Hungary
CROSSTALK BETWEEN PPARγ AND INFLAMMATORY SIGNALING: IDENTIFICATION OF STAT6
AS A LICENSING FACTOR FOR PPARγ-REGULATED GENE EXPRESSION IN MACROPHAGES
AND DENCDRITIC CELLS (Short talk)

Raphael Metivier

Interactions Cellulaires et Moléculaires, CNRS, University of Rennes, France
SPATIO-TEMPORAL REGULATIONS OF AN ESTROGEN-DEPENDENT GENE CLUSTER

Gordon Hager

Laboratory of Receptor Biology and Gene Expression, National Cancer Institute,Bethesda, USA
GENOME-WIDE NUCLEAR RECEPTOR/CHROMATIN INTERACTIONS

Muriel Le Romancer

INSERM U590, Lyon, France
THE ARGININE DEMETHYLASE JMJD6 IS INVOLVED IN ESTROGEN NON GENOMIC SIGNALING (Short talk)

Carlos P. Fitzsimons

LACDR/Leiden University, Leiden, The Netherlands
MicroRNA 18 AND 124a DOWN-REGULATE THE GLUCOCORTICOID RECEPTOR:
IMPLICATIONS FOR GLUCOCORTICOID RESPONSIVENESS IN THE BRAIN (Short talk)

Henk Stunnenberg

Department of Molecular Biology, Nijmegen Center for Molecular Life Sciences, Nijmegen,The Netherlands
GENOME WIDE APPROACHES TO DECIPHER NUCLEAR HORMONE RECEPTOR FUNCTION

Chair: Martin L. Privalsky

Department of Microbiology, University of California Davis, USA

Bert W. O’Malley

Department of Molecular and Cellular Biology, Baylor College of Medicine,Houston, TX USA
NR COACTIVATORS: PHYSIOLOGY OF DISEASE

Shigeaki Kato

Institute of Molecular and Cellular Biosciences, University of Tokyo,Tokyo, Japan
REGULATED HISTONE METHYLTRANSFERASE/DEMETHYLASE SUPPORTING NUCLEAR RECEPTOR FUNCTION

Michael Stallcup

Norris Comprehensive Cancer Center, University of Southern California,Los Angeles, California, USA
COORDINATION OF THE ACTIVITIES OF TRANSCRIPTIONAL COACTIVATOR COMPLEXES (Short talk)

Eckardt Treuter

Karolinska Institutet, Huddinge / Stockholm, Sweden
GPS2-DEPENDENT COREPRESSOR / SUMO PATHWAYS GOVERN ANTI-INFLAMMATORY ACTIONS
OF LRH-1 AND LXRs IN THE HEPATIC ACUTE PHASE RESPONSE (Short talk)

David J. Mangelsdorf

UT Southwestern Medical Center, Howard Hughes Medical Institute,Dallas, USA
NUCLEAR RECEPTORS, MAN, AND THEIR HERO THE CONQUEROR WORM

Didier Picard

Département de Biologie Cellulaire, University of Geneva, Switzerland
UNORTHODOX TWISTS IN THE REGULATION OF ERalpha LEVELS AND ACTIVITY

Jacques Drouin

Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Canada
TIF1beta IS A COACTIVATOR OF NGFI-B (Nur77), Nurr1 AND NOR1 (Short talk)

Malcolm G. Parker

Laboratory of Molecular Endocrinology, Imperial College,London, UK (Regular)
DIVERSE ACTIONS OF THE NUCLEAR RECEPTOR COREPRESSOR RIP140

Chair: Debabrata Chakravarti

Northwestern University Feinberg School of Medicine, Chicago, USA

Sebastiaan H. Meijsing

UCSF/ MPI Molecular Genetics, Berlin, Germany
THE BINDING SITE CODE: DNA-BINDING SITE SEQUENCE DIRECTS GLUCOCORTICOID RECEPTOR
STRUCTURE AND ACTIVITY

Natacha Rochel

IGBMC, Illkirch, France
SOLUTION STRUCTURES OF NUCLEAR RECEPTOR HETERODIMERS (Short talk)

Fraydoon Rastinejad

School of Medicine’s new Center for Molecular Design, University of Virginia, USA Regular
STRUCTURAL ORGANIZATION OF THE INTACT PPARgamma-RXRalpha HETERODIMER

Frank A. Claessens

Mol. Endo. Lab., Mol. Cell Biol. Departement, Leuven, Belgium
SPARKI: SPECIFICITY AFFECTING ANDROGEN RECEPTOR KNOCK-IN (Short talk)

Emily Jean Faivre

University of California, San Francisco
MODIFYING SF-1 TRANSCRIPTIONAL PROGRAMS BY SUMOYLATION (Short talk)

John Schwabe

Department of Biochemistry, University of Leicester, Leicester, UK
ASSEMBLY OF THE SMRT/NCoR TRANSCRIPTIONAL REPRESSION MACHINERY

Chin-Yo Lin

Brigham Young University, Provo, UT, USA
CONVERGENCE OF KEY CANCER-RELATED TRANSCRIPTIONAL REGULATORS INVOLVEMENT OF RUNX1
IN ESTROGEN RECEPTOR-MEDIATED TRANSCRIPTIONAL REPRESSION (Short talk)

Susanne Mandrup

University of Southern Denmark, Odense M, Denmark
GENOME-WIDE MAPPING OF LXR AND RXR BINDING SITES AND TARGET GENES IN MOUSE LIVER (Short talk)

Roland Schüle

Centre for Clinical Reserch, University of Freiburg, Germany
CHROMATIN MODIFICATIONS CONTOL PROSTATE CANCER GROWTH

Chair: Antonio Moschetta

Consorzio Mario Negri Sud, Santa Maria Imbaro, Italy

Patricia V. Elizalde

Institute of Biology and Experimental Medicine (IBYME), CONICET, Buenos Aires, Argentina
PROGESTERONE RECEPTOR RAPID ACTIVATION OF SIGNALING PATHWAYS MODULATE NONCLASSICAL
TRANSCRIPTIONAL EFFECTS

Günther Schütz

German Cancer Research Center (DKFZ), Heidelberg, Germany
THE ROLE OF THE NUCLEAR RECEPTOR TAILLES IN ADULT NEUROGENESIS AND
BRAIN TUMOR FORMATION (Short talk)

Orla M. Conneely

Baylor College of Medicine, Houston, USA
TUMOR SUPPRESSIVE MECHANISMS OF NR4A RECEPTORS IN HEMATOPOIETIC STEM CELLS (Short talk)

Walter Wahli

Center for Integrative Genomics, University of Lausanne, Switzerland
SUMOYLATED PPARalpha MEDIATES GENDER-SPECIFIC GENE REPRESSION

Adriana Maggi

Center of Excellence on Neurodegenerative Diseases of the University of Milan,Italy
ESTROGEN RECEPTOR IN LIVER: A SENSOR OF THE ENERGETIC STATUS?

Laure Quignodon

University of Lausanne, Lausanne, Switzerland
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR BETA/DELTE DELATION IMPAIRS AXON
OUTGROWTH AND LEADS TO PARTIALLY PENETRANT HYDROCEPHALUS (Short talk)

Michelina Plateroti

Molecular Biology and Biochemistry, Ecole Normale Supérieure, Lyon, France
THYROID HORMONE SIGNALING AND INTESTINAL PHYYSIOPATHOLOGY

Jan-Ake Gustafsson

Center for Nuclear Receptors and Cell Signaling, Dept of Biology and Biochemistry, University of Houston, Texas, USA
NOVEL ASPECTS OF LXR ACTION

Ana Aranda

Insituto de Investigaciones Biomédicas. CSIC, Madrid, Spain
THE THYROID HORMONE RECEPTORS ARE REQUIRED FOR NORMAL SKIN PROLIFERATION AND
EPIDERMAL STEM CELL FUNCTION (Short talk)

Daniel Metzger

Department of Physiological Genetics and Nuclear, Signaling, IGBMC,Strasbourg, France
THE TRANSCRIPTIONAL INTERMEDIARY FACTOR TIF2 PREVENTS MITOCHONDRIAL UNCOUPLING
IN SKELETAL MUSCLE MYOCYTES OF ADULT MICE

Thomas Perlmann

Department of Cell and Molecular Biology, Karolinska Institute,Stockholm, Sweden
NR4A ORPHAN RECEPTORS MEDIATE CREB-INDUCED NEUROPROTECTION

David D. Moore

Baylor College of Medicine, Houston, TX, USA
THERAPEUTIC APPLICATIONS OF LRH-1 AGONISTS