Programme

Saturday, October 25

14h00

Registration

18h00

Reception

19h30

Dinner

First session
Chair: Richard Zimmermann

21h00

Nica Borgese
Requirements for unassisted translocation of polar domains across lipid bilayers

21h30

Carol Deutsch
Tunnel Vision

22h00

Arnold Driessen
Mechanisms of Sec-mediated protein translocation and membrane protein insertion

Sunday, October 26

Second Session
Chair : Jerry Hazelbauer

9h00

Tassos Economou
Do not follow the leader

9h30

Thomas Becker
Novel insights into the assembly of the TOM complex

9h45

Wilbert Bitter
Type VII secretion systems in mycobacteria, role of ESX-5

10 00

Ralf Erdmann
The RING-finger peroxins function as E3-ligases required for receptor ubiquitination in peroxisomal protein import

10h30

Coffee

11 00

Justin Boddey
Defining the PEXEL: Role of the Plasmodium Export Element in trafficking parasite proteins to the infected erythrocyte

11h15

Bettina Bölter
Tim17/22/23 homologs in chloroplasts: function and significance in protein transport

11h30

Misha Bogdanov
Physiological basis for positive-inside rule: lipid-protein interactions affect the potency of charged residues as topological signals.

11h45

Thomas Brüser
Regulation of Tat transport

12h00

John Collier
Translocation of anthrax toxin across the endosomal membrane

12 15

Olivera Francetic
Testing the pseudopilus function in type II secretion

12h 45

Genviève Dujardin
Intragenic and extragenic compensatory mechanisms that improve respiratory functions in oxa1 point mutants

13h00

Lunch

14h30

Poster Session 1 and refreshments

Third Session
Chair: Paul Lazarow

17h00

Toshi Endo
Coordinated functions of mitochondrial translocator proteins for protein translocation across and into the membranes

17h 15

Reid Gilmore
In vivo kinetics of membrane protein integration

17h 45

Krisztian Fodor
Recognition of an unusual Peroxisomal Targeting Signal 1 by the import receptor Pex5p

18 00

Marc Fransen
Peroxisome membrane dynamics in cultured mammalian cells

18h15

Pierre Genevaux
A quality control network for presecretory proteins in Escherichia coli

18h30

Elzbeith Glaser
Import of amyloid beta peptide into mitochondria

18h45

Manu Hegde
Regulating entry of proteins into the ER

19h 15

Volkhard Helms
Statistical methods for helical transmembrane bundles: TMX and MINS

19h30

Business session

20h00

Dinner

Monday, October 27

Fourth Session
Chair: Wolf Kunau

8h30

Hannes Herrmann
The zinc-binding protein Hot13 is a component of the mitochondrial disulfide relay system

8h45

Steve High
The complexities of membrane protein biosynthesis at the ER

9h15

Kelly Hughes
Characterization of the flagellar secretion system

9h30

Carla Koehler
New small molecule tools for studying mitochondrial protein translocation

10h00

Andreas Kuhn
YidC binds its substrate proteins by the transmembrane regions TM1, TM3 and TM4

10h15

Trevor Lithgow
Assembling beta-barrel membrane proteins

10h30

Coffee Break

11h00

Matthias Müller
Molecular contacts along the Tat pathway

11h30

Masato Nakai
Protein import into chloroplasts is mediated by a 1-MD translocation complex at the inner envelope membrane

11h45

Walter Neupert
The TIM23 complex of mitochondria: Dissecting its functions in protein translocation and membrane insertion of precursor proteins

12h15

Davis Ng
Involvement of the greater endomembrane system in secretory protein quality control

12h 45

Ing-Marie Nilsson
Membrane integration efficiency of two ABC transporters, predicted to be structurally similar

13h00

Lunch

14h30

Posters and refreshments

Fifth Session
Chair: Ben Berks

17 00

Sjur Olsnes
Requirements for translocation of exogenous fibroblast growth factor into the cytosol and nucleus

17h15

Klaus Pfanner
Versatility of the mitochondrial protein import machinery

17h45

Ofrey Pines
The Mitochondrial Targeting Sequence tilts the balance between mitochondrial and cytosolic dual-localization

18h00

Departure for Chateau visit and dinner

Tuesday, October 28

Fifth Session (continued) Chariman Ben Berks

8h30

Lin Randall
Mapping the interaction surfaces on the proteins of the Sec system using site-directed spin labeling and EPR spectroscopy

9h00

Doron Rapaport
Evolutionary conserved sorting of beta-barrel membrane proteins

9h30

Colin Robinson
Quality control functions of the twin-arginine translocation (Tat) pathway in Escherichia coli

10h00

Karin Römisch
Interactors of the Sec61 complex in the ER membrane

10h 30

Coffee Break

Sixth Session
Chair Tony Pugsley

11h00

Dirk Schneider
Protein transport and targeting in cyanobacteria

11h15

Tom Silhavy
Suppression of Translocator Jamming by a Proto-oncogene Homologue in E. coli

11 h45

Irmi Sinning
Co- and post-translational protein targeting by the signal recognition particle (SRP)

12h00

Jürgen Soll
Metabolic redox regulation of protein import into chloroplasts

12h 30

Jack Taunton
Selective and promiscuous inhibitors of cotranslational translocation

13h00

Lunch

14h30

Poster session and refreshments

Sixth Session (continued)
Chair Tony Pugsley

17h00

Jan Tommassen
Species-specificity of the bacterial outer membrane protein assembly machinery

17h30

Cees van den Hondel
Upregulation of secretory pathway genes of Aspergillus niger by induction of protein secretion in chemostat cultures

17h45

Gunnar von Heijne
Dual-topology membrane proteins

18h15

Ute Vothknecht
Calcium/Calmodulin regulation: An eukaryotic addition to protein import into eukaryotic organelles

18h30

Gabriel Waksman
Fiber Formation Across the Bacterial Outer Membrane by the Chaperone/Usher Pathway

19h 00

Steve White
Stability and Helix-Gating of the SecYEG Translocon

19h15

Wolfgang Wintermeyer
Membrane targeting of translating ribosomes in E. coli

19h30

Richard Zimmermann
The protein translocase of the endoplasmic reticulum (ER) and related diseases

20 00

Dinner and party