| August 7 |
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Afternoon |
Arrival, registration |
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18:00 |
Cocktail |
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19:00-19:15 |
Opening Remarks |
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19:15-20:15 |
Keynote lecture
Chaired by: Joel Richter, UMass Medical School, Worcester, MA USA
Matthias Hentze, EMBL, Heidelberg, Germany
Regulatory RNA-binding proteins: from mechanistic reductionism to complete mRNA interactomes |
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20:30 |
Dinner |
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| August 8 |
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Session I: Post-Transcriptional gene regulation mechanisms
Chaired by: Martine Simonelig, CNRS, Montpellier |
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09:00-09:30 |
Joel Richter, UMass Medical School, Worcester
CPEB Control of mRNA Localization and Cell Polarity |
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09:30-10:00 |
Anne Ephrussi, EMBL, Heidelberg
oskar RNP assembly and transport in the Drosophila oocyte |
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10:00-10:30 |
Paul Macdonald, University of Texas, Austin
Regulation of, and by, Oskar mRNA |
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10:30-11:00 |
Coffee break |
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10:00-11:30 |
Paul Lasko, McGill University, Montreal
A role for variant ribosomes in germline development |
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11:30-11:45 |
Chao Jeffrey, Albert Einstein College of Medicine, New York
ZBP1 KH34 consensus RNA-binding site identifies post-transcriptional regulatory networks |
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11:45-12:00 |
Antonia Ratti, Istituto Auxologico Italiano, University of Milan Medical School
Post-transcriptional regulation of VEGF and PGRN gene expression by TDP-43 RNA-binding protein |
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12:00-12:15 |
Dierk Niessing, Institute of Structural Biology,Helmholtz Zentrum, München
Specific recognition of mRNAs for thei localization is achieved during the final mRNP maturation step in the cytoplasm |
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12:15-12:30 |
Mordechai Choder, Technion - Israel Institute of Technology, Haifa
"Mating bodies" function in mRNA transport, localization and local translation during mating in yeast |
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12:30-14:00 |
Lunch |
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14:00-15:00 |
Free Discussion |
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SESSION II: NON CODING RNAs
CHAIRED BY: CATHERINE RABOUILLE, HUBRECHT INSTITUTE FOR DEVELOPMENTAL BIOLOGY AND STEM CELL RESEARCH, UTRECHT |
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15:00-15:30 |
William Theurkauf, University of Massachusetts Medical School
UAP56 links heterochomatic clusters to the perinuclear piRNA biogenesis machinery |
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15:30-16:00 |
Martine Simonelig, Institut de Genetique Humaine/CNRS, Montpellier
mRNA regulation by deadenylation in the Drosophila germline and early embryo |
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16:00-16:30 |
Haifan Lin, Yale University, New Haven
The Yb Body, a Major Site for piRNA Biogenesis and a Gateway for Piwi Expression and Transport to the Nucleus in Somatic Cells |
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16:30-17:00 |
Break |
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17:00-17:30 |
Elisa Izaurralde, Max Planck Institute for Developmental Biology, Tübingen
GW182 proteins recruit cytoplasmic deadenylase complexes to miRNA targets |
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17:30-17:45 |
Michael Blower, Mass. General Hospital/Harvard Genetics Department, Boston
ESCRT-II links RNA localization to endosomal trafficking |
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17:45-18:00 |
Kim Raab-Graham, University of Texas at Austin
mTOR Serves as a Switch for Dendritic Excitability by the Reversible binding of miR-129 and HuD to Kv1.1 mRNA |
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18:00-18:30 |
Ruth Lehmann, Skirball Institute, NYU School of Medicine
Translational repression in germ line development |
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18:30-20:30 |
Poster Session I (red) |
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20:30 |
Dinner |
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| August 9 |
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SESSION III: RNA BIOINFORMATICS, LOCALIZATION SIGNALS AND mRNP STRUCTURE
CHAIRED BY: HAIFAN LIN, YALE UNIVERSITY |
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09:00-09:30 |
Yishi Jin, University of California, San Diego
Local translation in axon regeneration in C. elegans |
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09:30-10:00 |
Cedric Notredame, Centro de Regulacio Genomica, Barcelona
Finding and Multiply Aligning RNA sequences |
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10:00-10:15 |
Stewart Stevens, University of Otago, Dunedin
Bioinformatic approaches to the identification of localisation elements. |
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10:15-10:30 |
Fulvia Bono, Max Planck Institute for Developmental Biology, Tübingen
Structural studies of the cup-eIF4E complex |
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10:30-11:00 |
Coffee Break |
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SESSION IV: NEW FRONTIERS IN IMAGING VISUALIZING RNA LOCALIZATION IN LIVING CELLS
CHAIRED BY: TALILA VOLK, WEIZMANN INSTITUTE OF SCIENCE, REVOHOT |
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11:00-11:30 |
Ernst Stelzer, Goethe-University Frankfurt
Light sheet-based fluorescence microscopy (LSFM) reduces phototoxic effects providing new means for modern life sciences |
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11:30-12:00 |
David Ish-Horowicz, CR-UK London Research Institute
Genetic screen for novel factors regulating gurken transcript localisation in the Drosophila oocyte |
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12:00-12:15 |
Arne Gennerich, Albert Einstein College of Medicine, Bronx
Toward a unified walking model for cytoplasmic dynein |
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12:15-12:30 |
Jason Casolari, Stanford University
Live-Cell Super-Localization Microscopy of Localized mRNA Dynamics |
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12:30-14:00 |
Lunch |
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14:30-16:30 |
Hot Topic Session |
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16:30-19:00 |
Poster Session II (green) |
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19:00-20:30 |
Dinner |
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| August 10 |
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SESSION V: CELL POLARITY AND DEVELOPMENT I
CHAIRED BY: ARNE GENNERICH, ALBERT EINSTEIN COLLEGE OF MEDICIN, BRONX |
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09:00-09:30 |
Catherine Rabouille, Hubrecht Institute for developmental biology and stem cell research, Utrecht
dgrasp mRNA expression and localisation in the Drosophila epithelium during remodeling |
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09:30-10:00 |
Elisabeth Gavis, Princeton University
Function and regulation of Nanos and Pumilio in neuronal morphogenesis |
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10:00-10:30 |
Kimberly Mowry, Brown University
Directing Traffic during RNA Localization in the Cell Cytoplasm |
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10:30-11:00 |
Coffee break |
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11:00-11:30 |
Mani Ramaswami, Trinity College Dublin
mRNA regulation at identified synapses during learning |
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11:30-11:45 |
Michael Sheets, University of Wisconsin-Madison
Spatially regulated translation by Bicaudal-C controls Nodal signaling and cell fate determination during vertebrate development |
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11:45-12:00 |
Naohito Takatori, Osaka University
The mechanism of polarized nuclear migration that separates mesoderm and endoderm fates in ascidian embryos |
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12:00-13:00 |
Lunch |
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13:00-18:30 |
Excursion |
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SESSION VI: mRNPs LOCALIZATION, MEMBRANE TRAFFICKING AND SIGNAL TRANSDUCTION
CHAIRED BY: KIMBERLY MOWRY, BROWN UNIVERSITY |
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18:30-19:00 |
Akira Nakamura, RIKEN Center for Developmental Biology, Kobe
Protection of germ plasm RNAs from miRNA-mediated degradation in Drosophila primordial germ cells |
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19:00-19:30 |
Talila Volk, Weizmann Institute of Science, Rehovat
MAPK/ERK-dependent phosphorylation of Held Out Wing (HOW) alters its activity in controlling RNA metabolism |
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19:30-20:00 |
Ilan Davis, University of Oxford
The mechanism of mRNA transport and localised translation in the Drosophila neuromuscular junction |
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20:00-20:15 |
Orna Amster-Choder, Hebrew University, Jerusalem
Translation-independent localization of mRNA in E. coli |
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20:15-20:30 |
Tomas Aragon, Center for Applied Medical Research, Pamplona
Targeting of HAC1 mRNA to endoplasmic reticulum stress signaling foci |
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20:30 |
Dinner |
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| August 11 |
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SESSION VII: mRNA LOCALIZATION AND TRANSLATIONAL CONTROL IN NEURONS
CHAIRED BY: PETER SARNOW, STANFORD UNIVERSITY |
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09:00-09:30 |
Kelsey Martin, UCLA
Synapse-specific translational regulation |
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09:30-10:00 |
Christine Holt, University of Cambridge
RNA-based control of axon guidance |
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10:00-10:30 |
Claudia Bagni, Catholic University of Leuven/University of Rome Tor Vergata
mRNA metabolism in Fragile X related diseases |
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10:30-11:00 |
Coffee break |
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11:00-11:30 |
Michael Kiebler, Medical University of Vienna
Neuronal RNA granules and their role in dendritic RNA localization |
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11:30-12:00 |
Erin Schuman, Max Planck Institute for Brain Research, Frankfurt
The local transcriptome in hippocampal neurons |
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12:00-12:15 |
Catia Andreassi, University College London
NGF-dependent mRNA localization in axons of primary sympathetic neurons |
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12:30-14:00 |
Lunch |
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14:30-16:00 |
Business Meeting |
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SESSION VIII: CELL POLARITY AND DEVELOPMENT II
CHAIRED BY: CHRISTINE HOLT, UNIVERSITY OF CAMBRIDGE |
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16:00-16:30 |
Oswald Steward, University of California, Irvine
Title missing |
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16:30-17:00 |
Magdalena Zernicka-Goetz, University of Cambridge
Cell polarization dependent asymmetric inheritance of mRNA for Cdx2 during the first fate decision in the mouse embryo |
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17:00-17:30 |
Simon Bullock, MRC Laboratory of Molecular Biology, Cambridge
In vivo and in vitro assays reveal complex interplay between different microtubule-based motors on single mRNA molecules |
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17:30-18:00 |
Howard Lipshitz, University of Toronto
Post-transcriptional Control During the Maternal-to-Zygotic Transition in Drosophila |
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19:30 |
Farewell Banquet |
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| August 12 |
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SESSION IX: RNA TRANSPORT, TRANSLATIONAL CONTROL AND DISEASE
CHAIRED BY: ELISABETH GAVIS, PRINCETON UNIVERSITY |
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09:00-10:00 |
Keynote lecture
Roy Parker, University of Arizona, Tucson
The eukaryotic mRNA cycle: Movement of yeast mRNAs between polysomes, stress granules, and P-bodies and its role in the control of translation and degradation |
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10:00-10:30 |
Peter Sarnow, Stanford University
Modulation of Hepatitis C Virus and Insig1 RNA Abundances by a Specialized MicroRNA 122 Complex |
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10:30-11:00 |
Melissa Moore, University of Massachusetts Medical School, Worcester
Ribonucleoprotein export via nuclear envelope budding |
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11:00-11:15 |
Ranjan Perera, Sanford-Burnham Medical Research Institute, Orlando
The melanoma-upregulated long noncoding RNA SPRY4-IN1 modulates apoptosis and invasion |
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11:15-11:30 |
Claudia Fallini, Emory University, Atlanta
The Spinal Muscular Atrophy Disease Protein SMN Associates with mRNA-Binding Proteins and Regulates the Assembly and Transport of RNA Granules in Motor Neuron Axons |
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11:30-12:00 |
Discussion and closing remarks |
