Conference Series

European Molecular Biology Organization

CANCER PROTEOMICS 2009:

Mechanistic Insights, Technological Advances

& Molecular Medicine



 

 

 


8th - 11th June , 2009 | Dublin |Ireland

Programme


Download latest programm- June '09: (word.doc)
 

Location: O'Reilly Hall - University College Dublin, Belfield, Dublin 4, Ireland

 
     

Monday, 8th June

 

09.30 - 12.30

Oncoproteomics Educational Symposium (Chaired by Mike Dunn)
Supported by the Irish Association for Cancer Reseach
Location: UCD Conway Institute

 

12.00 - 13.00

Registration for Main Conference in O’Reilly Hall

 

13.00

OPENING OF CONFERENCE

 

13.00 - 13.15

Welcome and Opening Remarks:
William Gallagher – UCD Conway Institute, Ireland

 

 

Session 1 – Signalling and Systems Biology
Chaired by:   Walter Kolch

 

13.15 - 14.00

Opening Keynote Lecture:
Ruedi Aebersold – Swiss Federal Institute of Technology, Switzerland
“Plasma protein biomarker discovery and the PeptideAtlas"

 

14.00 - 14.30

Walter Kolch - Cancer Research UK Beatson Laboratories, UK
“Signalling Networks and Systems Biology”

 

14.30 - 15.00

Coffee Break/Trade Exhibition

a

15.00 - 15.30

Hubert Hondermarck, INSERM-University of Lille, France
“Cancer cell signaling: prospects of proteomics and challenges of biological complexity””

 

15.30 - 16.00

John Quackenbush – Dana-Farber Cancer Institute, USA                  
“Computational Approaches to Creating Network Models”

 

16.00 - 16.20

Emerging Investigator talk 1

Sara Zanivan - Max Planck Institute for Biochemistry, Germany
Protein Phosphorylation and Signalling”

 

16.30 - 18.30

WELCOME RECEPTION [Held in Poster Area]

a
 

 

 

Tuesday, 9th June

 

Session 2 – Proteomics for Mechanistic Insight into Cancer
Chaired by:   Mike Dunn

 

09.30 - 10.00

Paul Tempst – Memorial Sloan-Kettering Cancer Center, USA
“Blood-based exopeptidase activities as biomarkers for cancer”

 

10.00 - 10.30

Connie Jimenez - VUmc-Cancer Center, Amsterdam, The Netherlands (confirmed)
Proteomics targeted to sub-cellular compartments and secretomes
and integration with genomics for candidate biomarker discovery in colorectal cancer”

 

10.30 - 11.10

Coffee break/Trade exhibition

a

11.10 - 11.40

Richard Simpson – Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Australia
“Secretome-based Proteomic Strategies for Uncovering New Biomarkers for Colorectal Cancer”

 

11.30 - 12.10

Lukas Huber - Biocenter of the Medical University Innsbruck, Austria
“Analysis of MAPK signaling by Phosphoproteomics and Chemical Genetics”

 

12.10 - 12.30

Emerging Investigator/Short Talk 2
Filip Golebiowski - University of Dundee, UK
“System-wide analysis of changes to the SUMO2 proteome in response to heat-stress”

 

12.30 - 14.05

Lunch/Poster Session I

a

 

Session 3 – Array-Based Technologies
Chaired by:   Carl Borrebaeck

 

14.05 - 14.35

Carl Borrebaeck – Lund University, Sweden
“Diagnostic and predictive serum biomarkers in oncology”

 

14.35 - 15.05

Dolores Cahill – UCD Conway Institute, Ireland
“Profiling the Autoantibody Repertoire – overview of biomedical and diagnostic applications”

 

15.05 - 15.45

Coffee Break/Trade Exhibition

a

15.45 - 16.15

Stephen Hewitt – Advanced Technology Center - National Cancer Institute, USA
“Tissue Microarrays and Image Analysis”

 

16.15 - 16.45

Fredrik Ponten – University of Uppsala, Sweden
“A Human Protein Atlas”

 

16.45 - 17.05

Emerging Investigator/Short Talk 3

Darran O’Connor – UCD Conway Institute, Ireland
"The Cocaine and Amphetamine-Regulated Transcript (CART) is an Independent Marker of Breast Cancer Outcome and Predicts Response to Tamoxifen"

 

19.30

EVENING SOCIAL EVENT

a
 

 

 

Wednesday 10th

 

Session 4 – Informatics Approaches and Computational Proteomics
Chaired by:   Rolf Apweiler

 

09.30 - 10.00

Rolf Apweiler – European Bioinformatics Institute, UK
“Bioinformatics Infrastructure for Proteomics: Status of Database and Standards Development”

 

10.00 - 10.30

Peadar O’Gaora – UCD Conway Institute, Ireland
“High-Throughput Identification of Alternative Splice Isoforms from Proteomic Data”

 

10.30 - 11.10

Coffee Break/Trade Exhibition

a

11.10 - 11.40

Steven Potts – Aperio, USA
“Automated Analysis of Immunohistochemical Staining”

 

11.40 - 12.10

Richard Caprioli – Vanderbilt University, USA
Direct protein analysis in biopsy tissue using imaging/profiling mass spectrometry”

 

12.10 - 12.30

Emerging Investigator/Short Talk 4

Nicholas Gauthier – cBio Memorial Sloan Kettering Cancer Center
Models from experiments: combinatorial drug perturbations of cancer cells”

 

12.30 - 14.05

Lunch/Poster Session II

a

 

Bioethics Session: “Biological Collections: Who Owns and Who Profits?”
Chaired by:   William Watson

 

14.05 - 14:40

Elaine Kay - Royal College of Surgeons in Ireland, Ireland

 

14:40 - 15:15

David Smith - Royal College of Surgeons in Ireland, Ireland

 

 

Session 5 – Proteomics in Development of Anti-Cancer Therapeutics
Chaired by:   William Gallagher

 

15.20 - 15.50

Renata Pasqualini – MD Anderson Cancer Center, USA
“Ligand-directed therapy and molecular imaging based on in vivo phage display technology”

 

15.50 - 16.20

Mark O’Connor - KuDOS Pharmaceuticals, UK
“Proteomics in Anti-Cancer Drug Development”

 

16.20 - 17.00

Coffee Break/Trade Exhibition

a

17.00 - 17.30

Hanno Langen - F. Hoffmann-La Roche, Switzerland
““From Biomarker Discovery to Validation in Clinical Sample - Towards Screening Markers for Colon Rectal Cancer”

 

17.30 - 18.00

Bernhard Kuster - Technical University of Munich
“A quantitative chemical proteomics approach reveals novel modes of action of clinical ABL kinase inhibitors”

 

18.00 - 18.20

Emerging Investigator/Short Talk 5

Ariel Cohen  – Weizmann Institute of Science, Israel

“Dynamic Proteomics of Individual Cancer Cells in Response to a Drug”
 

19.30

CONFERENCE DINNER AND TRAVEL PRIZE AWARDS

a

 

 

 

Thursday 11th June

 

Session 6 – Cancer Biomarker Development
Chaired by:   Dolores Cahill

 

09.00 - 09.30

Michael Gillette – Broad Institute of MIT and Harvard, USA
   “Progress Toward a Biomarker Discovery-to-Development Pipeline in Clinical Proteomics

 

09.30 - 10.00

Amanda Paulovich - Fred Hutchinson Cancer Research Center, USA

“Integrated Pipeline for Mass Spectrometry-Based Discovery and Confirmation of Protein Biomarkers Demonstrated in a Mouse Model of Breast Cancer”

 

10.00 - 10.30

Doug Ross – Applied Genomics, USA (confirmed)
“Immunohistochemical Surrogates of Gene Expression Profiles”

 

10.30 - 11.00

Coffee Break/Trade Exhibition

a

11.00 - 11.45

Keynote Lecture:
Sam Hanash - Fred Hutchinson Cancer Research Center, USA
“Application of proteomics to cancer molecular diagnostics”

 

11.45 - 12.15

Julio Celis – Danish Centre for Translational Breast Cancer Research, Denmark
“Proteomic Analysis of the Tumor-Host Microenvironment”

 

12.15 - 12.45

Roz Banks – Cancer Research UK Clinical Centre, Leeds
“New Markers in Renal Cancer and a Route to the Clinic?”

 

12.45 - 12.55

Closing Remarks:
Mike Dunn – UCD Conway Institute, Ireland

 

12.45

CLOSE OF CONFERENCE

 

 

 

 

 

 

 

 

 

 

 

 

 

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