Programme
Day 1 (19th) | Day 2 (20th) | Day 3 (21st) | Day 4 (22nd) | Day 5 (23rd) |
||
| Download Programme (pdf) | ||
Afternoon: |
|
|
14:00-18:00 |
Arrival and check-in |
|
Evening: |
|
|
18:45-19:45 |
Dinner |
|
20:00-20:10 |
Welcome, Introduction |
|
20:10-22:20 |
Session 1 - Early DNA and chromosome events |
 |
20:10-20:30 |
Scott Keeney (Memorial Sloan-Kettering Cancer Center, New-York, USA) |
|
|
« Mechanism and regulation of meiotic double-strand break formation » |
|
20:30-20:40 |
Discussion |
|
20:40-20:55 |
Dean Dawson (Oklahoma Medical Research Foundation, Oklahoma city, USA) |
|
|
« Meiotic cohesins and the synaptonemal complex protein, Zip1, promote associations of non-homologous centromeres while chromosome arms engage in homologous interactions » |
|
20:55-21:05 |
Discussion |
|
21:05-21:20 |
Franz Klein (University of Vienna, Austria) |
|
|
« DSB-promoting factors link DSB formation with chromosome structure » |
|
21:20-21:30 |
Discussion |
|
21:30-21:45 |
Kunihiro Ohta (Faculty of Life Sciences, University of Tokyo, Japan) |
|
|
« Control of meiotic DSB formation by chromatin, cohesin, and Spo11-accessory proteins » |
|
21:45-21:55 |
Discussion |
|
21:55-22:10 |
Alain Nicolas (Institut Curie, Paris, France) |
|
|
Histone modifications and meiotic recombination initiation sites » |
|
22:10-22:20 |
Discussion |
|
|
||
Morning: |
|
|
7:00-8:30 |
Breakfast |
|
8:30-12:00 |
Session 2- Mechanisms of recombination |
|
8:30-8:50 |
Gerry Smith (Fred Hutchinson Cancer Research Center, Seattle, USA) |
|
|
«Mechanism and control of meiotic recombination in S. pombe: from DSBs to RNAi » |
|
8:50-9:00 |
Discussion |
|
9:00-9:15 |
Bernard de Massy (Institut de Génétique Humaine, CNRS, Montpellier, France) |
|
|
«Genome wide control of the distribution of meiotic recombination in mice » |
|
9:15-9:25 |
Discussion |
|
9:25-9:40 |
Dan Camerini-Otero (Genetics and Biochemistry Branch, NIDDK, NIH, Bethesda, USA) |
|
|
« Meiotic Homologous Recombination and Pairing in Mice » |
|
9:40-9:50 |
Discussion |
|
9:50-10:15 |
Coffee break |
|
10:15-10:30 |
Neil Hunter (University of California, Davis, USA) |
|
|
« Implementing a Crossover Outcome During Meiotic Recombination. » |
|
10:30-10:40 |
Discussion |
|
10:40-10:55 |
Alexander Lorenz (University of Oxford, UK) |
|
|
« The human Holliday Junction resolvase GEN1 rescues the meiotic phenotype of a fission yeast mus81 deletion » |
|
10:55-11:05 |
Discussion |
|
11:05-11:20 |
Holger Puchta (Botanical Institute II, University of Karlsruhe, Germany) |
|
|
« Topoisomerase 3α and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thaliana » |
|
11:20-11:30 |
Discussion |
|
11:30-11:45 |
Adriana La Volpe (CNR Institute of Genetics and Biophysics, Naples, Italy) |
|
|
« Roles of FANCD2 ortholog in meiotic DSBs repair in Caenorhabditis elegans » |
|
11:45-11:55 |
Discussion |
|
12:30-13:30 |
Lunch |
|
Afternoon : |
|
|
14:00-16:00 |
Poster I (even numbers) |
|
|
Free time |
|
Evening: |
|
|
18:00-20:10 |
Session 3- Crossover control, part 1 |
|
18:00-18:20 |
Michael Lichten (National Cancer Institute, Bethesda, USA) |
|
|
« Efficient sister chromatid recombination during meiosis when homologous sequences are absent from the homolog » |
|
18:20-18:30 |
Discussion |
|
18:30-18:45 |
Rita Cha (MRC, London, UK) |
|
|
« Essential Roles of Mec1/Tel1 during Budding Yeast Meiosis » |
|
18:45-18:55 |
Discussion |
|
18:55-19:10 |
Paula Cohen (Cornell University, Ithaca, USA) |
|
|
« Crossover control in the mouse: a complex interplay between MUS81, BLM helicase, and the meiotic mismatch repair machinery » |
|
19:10-19:20 |
Discussion |
|
19:20-19:35 |
Jennifer Fung (University of California, San Francisco, USA) |
|
|
« Global Analysis of Crossover Control in Budding Yeast » |
|
19:35-19:45 |
Discussion |
|
19:45-20:00 |
Denise Zickler (Institut de Génétique et Microbiologie, Orsay, France) |
|
|
« Coming together is fraught with danger even for meiotic chromosomes » |
|
20:00-20:10 |
Discussion |
|
20:30 |
Dinner |
|
Morning: |
|
|
7:00-8:30 |
Breakfast |
|
8:30-12:00 |
Session 4- Crossover control, part 2 |
|
8:30-8:50 |
Sue Amstrong (University of Birmingham, UK) |
|
|
« Early Events in the Barley Meiotic Pathway » |
|
8:50-9:00 |
Discussion |
|
9:00-9:15 |
Nancy Kleckner (Harvard University, Boston, USA) |
|
|
« Meiotic sister/homolog relationships are governed by chiasma-dictated logic of recombinosome/structure interplay » |
|
9:15-9:25 |
Discussion |
|
9:25-9:40 |
Attila Toth (Institute of Physiological Chemistry, Dresden, Germany) |
|
|
« Mus musculus HORMAD1 and 2 mark unsynapsed meiotic chromosome axes and their removal from chromosomes in response to synapsis requires the TRIP13 AAA-ATPase » |
|
9:40-9:50 |
Discussion |
|
9:50-10:15 |
Coffee break + group photo |
|
10:15-10:30 |
Anne Villeneuve (Stanford University, USA) |
|
|
« Manipulation and Visualization of Recombination Events during C. elegans Meiosis » |
|
10:30-10:40 |
Discussion |
|
10:40-10:55 |
Barbara Meyer (Howard Hughes Medical Institute / U.C. Berkeley, USA) |
|
|
« Condensin Complexes Regulate DSB Distribution and thereby Crossover Frequency by Controlling Chromosome Structure » |
|
10:55-11:05 |
Discussion |
|
11:05-11:20 |
Christer Höög (Karolinska Institutet, Stokholm, Sweden) |
|
|
« Organization and function of the central element of the synaptonemal complex » |
|
11:20-11:30 |
Discussion |
|
11:30-11:45 |
Andreas Hochwagen (Whitehead Institute for Biomedical Research, Boston, USA) |
|
|
« Roles of the checkpoint phosphatase PP4 in premeiotic DNA replication and crossover interference » |
|
11:45-11:55 |
Discussion |
|
12:30-13:30 |
Lunch |
|
Afternoon : |
|
|
14:00-16:00 |
Poster II (odd numbers) |
|
|
Free time |
|
Evening : |
|
|
18:00-20:10 |
Session 5- Chromosome dynamics |
|
|
|
|
18:00-18:20 |
Yasushi Hiraoka (Osaka University, Japan) |
|
|
« A hot spot of homologous chromosome pairing in fission yeast » |
|
18:20-18:30 |
Discussion |
|
18:30-18:45 |
Julie Cooper (Cancer Research UK, London, UK) |
|
|
« Telomeric control of meiosis » |
|
18:45-18:55 |
Discussion |
|
18:55-19:10 |
Abby Dernburg (Howard Hughes Medical Institute/UC Berkeley, USA) |
|
|
« Coordination of pairing and synapsis in roundworms and flatworms » |
|
19:10-19:20 |
Discussion |
|
19:20-19:35 |
Verena Jantsch (University of Vienna, Dept. of Chromosome Biology Max F. Perutz Labs, Austria) |
|
|
« Alteration of nuclear envelope properties during the time of meiotic homologous pairing in C. elegans » |
|
19:35-19:45 |
Discussion |
|
19:45-20:00 |
Akira Shinohara (Institute for Protein Research, Osaka University, Japan) |
|
|
« Two cell cycle kinases, CDK (cyclin-dependent kinase) and DDK (Dbf4-dependent kinase), control chromosome dynamics during meiosis » |
|
20:00-20:10 |
Discussion |
|
20:30 |
Dinner |
|
Morning: |
|
|
7:00-8:30 |
Breakfast |
|
8:30-12:00 |
Session 6 - Chromosome segregation |
|
8:30-8:50 |
Kim Nasmyth (Dept of Biochemistry, Oxford University, UK) |
|
|
"Sister chromatid cohesion" |
|
8:50-9:00 |
Discussion |
|
9:00-9:15 |
Terry Orr-Weaver (Whitehead Institute, Dept. of Biology, MIT, Boston, USA) |
|
|
« Regulation of Centromere Cohesion in Drosophila » |
|
9:15-9:25 |
Discussion |
|
9:25-9:40 |
Yoshinori Watanabe (University of Tokyo, Institute of Molecular Cellular Bioscience, Japan) |
|
|
« Regulation of centromeric localization of shugoshin » |
|
9:40-9:50 |
Discussion |
|
9:50-10:15 |
Coffee break |
|
10:15-10:30 |
Monica Colaiacovo (Harvard Medical School, Boston, USA) |
|
|
« LAB-1 cooperates with cohesin to ensure accurate homolog segregation during meiosis I » |
|
10:30-10:40 |
Discussion |
|
10:40-10:55 |
Ounissa Aït-Ahmed (Institut de Génétique Humaine UPR 1142 CNRS, Montpellier, France) |
|
|
« Drosophila female meiosis I: Yemanuclein-alpha is a new synaptonemal complex associated protein required for chromosome segregation » |
|
10:55-11:05 |
Discussion |
|
11:05-11:20 |
Kim McKim (Rutgers University, Piscataway, USA) |
|
|
« Bi-orientation of bivalents before metaphase arrest in Drosophila oocytes » |
|
11:20-11:30 |
Discussion |
|
11:30-11:45 |
Marie-Hélène Verlhac (Laboratoire de Biologie du développement, UMR7622, Paris, France) |
|
|
« HURP is required for maintenance of meiotic spindle bipolarity » |
|
11:45-11:55 |
Discussion |
|
12:30-13:30 |
Lunch or lunchboxes |
|
Afternoon : |
|
|
12:30-18:00 |
Excursion to Avignon |
|
Evening: |
|
|
18:30-20:40 |
Session 7 - Progression through the meiotic cycle |
|
18:30-18:50 |
Masayuki Yamamoto (University of Tokyo Graduate School of Science, Japan) |
|
|
« Molecular basis for the selective elimination of meiosis-specific mRNAs in growing fission yeast cells » |
|
18:50-19:00 |
Discussion |
|
19:00-19:15 |
Sophie Rousseaux (INSERM U823 Institut Albert Bonniot, Grenoble, France) |
|
|
« Chromatin dynamics during spermatogenesis » |
|
19:15-19:25 |
Discussion |
|
19:25-19:40 |
Wolfgang Zacharie (MPI of Molecular Cell Biology and Genetics, Dresden, Germany) |
|
|
« Control of chromosome segregation by a meiosis-specific form of the APC/C » |
|
19:40-19:50 |
Discussion |
|
19:50-20:05 |
Katia Wassman (Laboratoire de Biologie du développement, UMR7622, France) |
|
|
« Cyclin A2 is required for the first meiotic division in mouse oocytes » |
|
20:05-20:15 |
Discussion |
|
20:15- 20:30 |
Raphaël Mercier (INRA SGAP, Versailles, France) |
|
|
« Turning meiosis into mitosis » |
|
20:30-20:40 |
Discussion |
|
21:00 |
Banquet |
|
|
|
|
Morning: |
|
|
7:00-9:00 |
Breakfast |
|
|
(check out time: 10:00) |
|
9:00-12:00 |
Session 8: |
|
9:00-9:20 |
Sam Schoenmakers (Erasmus University Medical Center, Rotterdam, Netherlands) |
|
|
« Meiotic silencing of sex chromosomes in the female avian germline » |
|
9:20-9:30 |
Discussion |
|
9:30-9:45 |
Jesus Page (Departamento de Biologia, Universidad Autonoma de Madrid, Spain) |
|
|
« Synapsis and transcriptional activity during mammalian meiosis: a comparative perspective » |
|
9:45-9:55 |
Discussion |
|
9:55-10:10 |
Aracely Lutes (Stowers Institute for Medical Research, Kansas City, USA) |
|
|
« The Mechanism of Meiosis in the Parthenogenetic Lizard Aspidoscelis neomexicana » |
|
10:10-10:20 |
Discussion |
|
10:20-10:50 |
Coffee break |
|
10:50-11:05 |
Simon Myers (University of Oxford, UK) |
|
|
« Recent human hotspot turnover reflects both cis and trans evolution » |
|
11:05-11:15 |
Discussion |
|
11:15-11:30 |
Graham Coop (University of California, Davis, USA) |
|
|
« Broad-scale recombination patterns underlying proper disjunction in humans » |
|
11:30-11:40 |
Discussion |
|
11:40-11:55 |
Laurent Duret (CNRS - Université Lyon 1, France) |
|
|
« Biased gene conversion and the evolution of human genomic landscapes » |
|
11:55-12:05 |
Discussion |
|
12:30-13:30 |
Lunch |
|
Afternoon: |
|
|
14:00 |
Departure to Avignon (TGV) or Marseille Airport |
|