Programme

Below is the outline format of the workshop programme (subject to change).
Monday, 16th June
1400	Departure by bus from Oslo Central Station
1800	Arrival in Geilo
1900	Buffet dinner
2015	Welcome
2030	Keynote Address John F.X. Diffley, Cancer Research UK Regulation of Replication Origin Activation during the Cell Cycle and in Response to DNA Damage

Tuesday, 17th June
Replication Forks I Session chair: Kirsten Skarstad
0830 – 0900	Ulrich Hübscher, University of Zürich Faithful DNA synthesis by human DNA polymerases over 8-oxo-guanine
0900 – 0930	EMBO YIP Lecture: Karim Labib, Cancer Research UK Regulating the progression of eukaryotic DNA replication forks
0930 – 0945	Erik Johansson, Umeä University The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA
0945 – 1015	Break
1015 – 1045	Antoine van Oijen, Harvard Medical School Under the Hood of the Replisome: A Single-Molecule View of DNA Replication
1045 – 1115	Bénédicte Michel, CNRS, Gif-sur-Yvette ruvA and ruvB mutants that resolve Holliday junctions but do not reverse replication forks
1115 – 1130	Francesca M. Pisani, Consiglio Nazionale Ricerche, Napoli Structure/function relationships of the Sulfolobus solfataricus MCM complex
1200 – 1400	Lunch break
Chromosome Segregation and Cell Division Session chair: Jeff Errington
1400– 1430	Piet de Boer, Case Western Reserve University School of Medicine Identification and properties of RodZ, a protein required for proper assembly of the MreB actin cytoskeleton in Escherichia coli
1430 – 1500	Rodney Rothstein, Columbia University Medical Center Kinetochore and spindle protein asymmetry defines a single yeast lineage
1500 – 1530	Tomoyuki Tanaka, University of Dundee Kinetochore capture and bi-orientation on the mitotic spindle
1530 – 1800	Break and Posters
1800 – 1815	Jean-Yves Bouet, CNRS, Toulouse Non-specific DNA binding of the Walker box ATPase partition protein SopA regulates polymerization and ATPase activity
1815 – 1830	Ram Madabhushi, Cornell University Differential Regulation of Topo IV by the actin homologue, MreB, in Escherichia coli
1830 – 1845	William Burkholder, Stanford University A gene that contributes to the coordination of cell division with DNA replication in Bacillus subtilis
1845 – 1900	Marcelo Nollman, INSERM and CNRS Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis
1900 – 1915	Zuzana Storchova, Max-Planck Institute of Biochemistry, Martinsried The role of Sgo1 and Bub1 in chromosome segregation in budding yeast
2000	Dinner

Wednesday, 18th June
Replication Forks II Session chair: Erik Boye
0830 – 0900	Marco Foiani, IFOM - FIRC, Milano Topological transitions at replicating chromosomes
0900 – 0930	Kenji Shimada, Friedrich Miescher Institute for Biomedical Research, Basel Ino80 chromatin remodeling complex promotes recovery of stalled replication forks
0930 – 1000	Break
Origins and Initiation I Session chair: John Diffley
1000 – 1030	Dale Wigley, CRUK Clare Hall Laboratories Structure and mechanism of an archaeal replication origin binding protein
1030 – 1100	Stephen Bell, Oxford University Replication of archaeal chromosomes
1100 – 1130	Julian Blow, University of Dundee The use of dormant origins can help ensure complete replication of genomic DNA
1130 – 1145	Mirit Aledjem, NCI, NIH Roles for replicator sequences and chromatin modifiers in modulating mammalian DNA replication
1200 – 1400	Lunch break
1400 – 1430	Crisanto Gutierrez, Centro de Biologia Molecular "Severo Ochoa", Madrid Dynamics of pre-RC components and their role in DNA replication and endocycle control during Arabidopsis development
1430 – 1500	David Shore, University of Geneva Telomere length regulation: cross-talk with nearby DNA replication origins
1500 – 1530	Johannes Walter, Harvard Medical School Replication-dependent mechanisms that insure genome stability
1530 – 1545	María Gómez, Instituto de Microbiología Bioquímica, Salamanca Rereplication of short DNA regions during S phase in human cells
1545 – 1800	Break and Posters
1830	Buffet Dinner
2000	Excursion (weather permitting)

Thursday, 19th June
Origins and Initiation II Session chair: Ueli Hübscher
0830 – 0900	Hisao Masai, Tokyo Metropolitan Institute of Medical Science Regulation of establishment and maintenance of replication fork by Cdc7 kinase
0900 – 0930	Tsutomu Katayama, Kyushu University Analysis on mechanisms of ATP-DnaA assembly on oriC and duplex unwinding
0930 – 0945	Dhruba Chattoraj, NIH/NCI, Center for Cancer Research Replication control of the Vibrio cholerae chromosome II: An elaboration on the plasmid paradigm
0945 – 1000	Yoshiharu Yamaichi, Brigham and Women's Hospital/Harvard Medical School Biochemical, genetic and chemical genetic dissection of RctB, the initiator protein of Vibrio cholerae chromosome II replication
1000 – 1030	Break
1030 – 1100	Jeff Errington, Newcastle University Dynamic control of the DNA replication initiation protein DnaA by Soj (ParA)
1100 – 1130	Peter Graumann, University of Freiburg Cell cycle-dependent spatial sequestration of the DnaA replication initiator protein in Bacillus subtilis
1130 – 1200	Kirsten Skarstad, Institute for Cancer Research, Oslo Organization of replication forks by the SeqA protein
1200 – 1400	Lunch break
Chromosome Structure Session chair: Peter Graumann
1400– 1430	Frank Uhlmann, Cancer Research UK, London Establishment of sister chromatid cohesion during DNA replication
1430 – 1500	Camilla Sjøgren, Karolinska Institutet, Stockholm The SMC5/6 protein complex – a chromosome length-dependent function?
1500 – 1515	Ana-Maria Farcas, University of Oxford Does cohesin topologically entrap sister DNAs?
1515 – 1530	Armelle Legronne, Institut de Genetique Humaine CNRS, Montpellier The Ctf18-Ctf8-Dcc1 complex is required for the maintenance of fork integrity and checkpoint activation
1530 – 1800	Break and Posters
1800 – 1830	David Sherratt, University of Oxford Independent positioning and action of replication forks in live Escherichia coli
1830 – 1900	Sigal Ben-Yehuda, The Hebrew University of Jerusalem Spatial organization of a replicating bacterial chromosome
1900 – 1915	Frédéric Boccard, Centre de Génétique Moléculaire du CNRS, Gif-sur-Yvette Organizing the Ter macrodomain of the E. coli chromosome
2000	Banquet Dinner

Friday, 20th June
10:00	Departure by bus to Oslo
14:00	Arrival at Oslo Central Station

Co-Sponsors

Programme